ID   A0A2R8ZYW5_PANPA        Unreviewed;      1019 AA.
AC   A0A2R8ZYW5;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=TOG array regulator of axonemal microtubules 2 {ECO:0000313|Ensembl:ENSPPAP00000008937.1};
GN   Name=TOGARAM2 {ECO:0000313|Ensembl:ENSPPAP00000008937.1};
OS   Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000008937.1, ECO:0000313|Proteomes:UP000240080};
RN   [1] {ECO:0000313|Ensembl:ENSPPAP00000008937.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AJFE02095295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02095296; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02095297; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02095298; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003827189.1; XM_003827141.2.
DR   AlphaFoldDB; A0A2R8ZYW5; -.
DR   Ensembl; ENSPPAT00000031577.1; ENSPPAP00000008937.1; ENSPPAG00000027706.1.
DR   GeneID; 100979549; -.
DR   KEGG; pps:100979549; -.
DR   CTD; 165186; -.
DR   GeneTree; ENSGT00940000156217; -.
DR   OMA; TPSKGWQ; -.
DR   OrthoDB; 3679265at2759; -.
DR   Proteomes; UP000240080; Unplaced.
DR   Bgee; ENSPPAG00000027706; Expressed in heart and 5 other cell types or tissues.
DR   GO; GO:0015630; C:microtubule cytoskeleton; IEA:UniProt.
DR   GO; GO:0008017; F:microtubule binding; IEA:UniProt.
DR   GO; GO:0051494; P:negative regulation of cytoskeleton organization; IEA:UniProt.
DR   GO; GO:1902904; P:negative regulation of supramolecular fiber organization; IEA:UniProt.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024395; CLASP_N_dom.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR21567; CLASP; 1.
DR   PANTHER; PTHR21567:SF42; TOG ARRAY REGULATOR OF AXONEMAL MICROTUBULES PROTEIN 2; 1.
DR   Pfam; PF12348; CLASP_N; 1.
DR   SMART; SM01349; TOG; 2.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT   DOMAIN          481..716
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   DOMAIN          762..998
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REGION          29..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          132..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          280..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          991..1019
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1005..1019
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1019 AA;  110991 MW;  FA089FDD845396D8 CRC64;
     MGTRDDVPEA KVLVPVAVYC GSIPRTSAGP RVLPPGSINS SLPHGEGSLQ PEPRALLNNE
     EPSQLLSGLG QLGGLKLDTP SKGWQARNGH PRNLRALSLG AQPLVLLPSP ESEANSVARD
     TIQIKDKLKK RRLSEGLAAS SRDSLDPGGG PQGVPLHSTI PRATSQRLLR VPRLMPPIQS
     IPTTPEASGV KEKGLDLPGS IPGPHELRPG AQEAQISRQY LHCNDEKMQK SLGAIVIPPI
     PKARTVAATP SRVPGSLPSP LPPGQGVLTG LRAPRMRLAR GSGPWERTPA SLEPKPLASP
     IRNRPAAAKK PALPFSQSAP MLTAFSFDCA KEACPPLKEE DQKEIGTKIQ VTISKSAQEK
     MRLKQMKEME LLRRLEEPKT GQELTPQGLG SQRAFMKEGL LPLRGSRTLS VPTRLSGPRR
     NDVGVILRKW ASRASLPSIP VSRQEPRFAR HASANSLPAV LTLGSPEWEE EEEMDLRACK
     ELRPFSNPEL GLRDALQCLN SSDWQMKEKG LVSIQRLAAC HSEVLTGRLH DVCLAVTGEV
     TNLRSKVSHL AISTLGDLFQ ALKKNMDQEA EEIARCLLQK MADTNEFIQR AAGQSLRAMV
     ENVTLARSLV VLTSAGVYHR NPLIRKYAAE HLSAVLEQIG AEKLLSGTRD STDMLVHNLV
     RLAQDSNQDT RFYGRKMVNI LMANTKFDAF LKQSLPSYDL QKVMAAIKQR GIEDNDELPS
     AKGRKVLRSL VVCENGLPIK EGLSCNGPRL VGLRSTLQGR GEMVEQLREL TRLLEAKDFR
     SRMEGVGQLL ELCKAKPELV AAHLVQVFDA FTPRLQDSNK KVNQWALESL AKMIPLLKES
     LHPMLLSIII AVADNLNSKN SGIYAAAVAV LDAMVESLDN LCLLPAFAGR VRFLSGHAVL
     DVTDRLAVLV ASVYPRKPQA VERHVLPILW HFLNTATGNG TLPGPSGNIR GVVCRLSRSL
     QEHMGSRLLD FAASQPKHVL KTLQELLDSE SLGGSRKATD RGVAPDSKTT GSSYPFQLD
//