ID A0A2R9A090_PANPA Unreviewed; 497 AA.
AC A0A2R9A090;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Ganglioside induced differentiation associated protein 2 {ECO:0000313|Ensembl:ENSPPAP00000010671.1};
GN Name=GDAP2 {ECO:0000313|Ensembl:ENSPPAP00000010671.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000010671.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000010671.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000010671.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GDAP2 family.
CC {ECO:0000256|ARBA:ARBA00008355}.
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DR EMBL; AJFE02017254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02017255; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02017256; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9A090; -.
DR STRING; 9597.ENSPPAP00000010671; -.
DR Ensembl; ENSPPAT00000033323.1; ENSPPAP00000010671.1; ENSPPAG00000028536.1.
DR GeneTree; ENSGT00940000156336; -.
DR OMA; VHLFRYV; -.
DR Proteomes; UP000240080; Chromosome 1.
DR Bgee; ENSPPAG00000028536; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0032526; P:response to retinoic acid; IEA:Ensembl.
DR CDD; cd02905; Macro_GDAP2-like; 1.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR002589; Macro_dom.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR035793; Macro_GDAP2.
DR PANTHER; PTHR11106; GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR11106:SF72; GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF01661; Macro; 1.
DR SMART; SM00506; A1pp; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR PROSITE; PS51154; MACRO; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 43..224
FT /note="Macro"
FT /evidence="ECO:0000259|PROSITE:PS51154"
FT REGION 253..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 56239 MW; 00039A099F35C116 CRC64;
MDPLGAPSQF VDVDTLPSWG DSCQDELNSS DTTAEIFQED TVRSPFLYNK DVNGKVVLWK
GDVALLNCTA IVNTSNESLT DKNPVSESIF MLAGPDLKED LQKLKGCRTG EAKLTKGFNL
AARFIIHTVG PKYKNRYRTA AESSLYSCYR NVLQLAKYEQ SMSSVGFCVI NSAKRGYPLE
DATHIALRTV RRFLEIHGET IEKVVFAVSD LEEGTYQKLL PLYFPRSLKE ENRSLPYLPA
DIGNAEGEPV VPERQIRISE KPGAPEDNQE EEDEGLGVDL SFIGSHAFAR MEGDIDKQRK
LILQGQLSEA ALQKQHQRNY NRWLCQARSE DLSDIASLKA LYQTGVDNCG RTVMVVVGRN
IPVTLIDMDK ALLYFIHVMD HIAVKEYVLV YFHTLTSEYN HLDSDFLKKL YDVVDVKYKR
NLKAVYFVHP TFRSKVSTWF FTTFSVSGLK DKIHHVDSLH QLFSAISPEQ IDFPPFVLEY
DARVRSTRSS PSPGMVY
//
