ID A0A2R9A239_PANPA Unreviewed; 665 AA.
AC A0A2R9A239;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Zinc finger protein 333 {ECO:0000313|Ensembl:ENSPPAP00000011342.1};
GN Name=ZNF333 {ECO:0000313|Ensembl:ENSPPAP00000011342.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000011342.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000011342.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000011342.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02020170; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02020171; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02020172; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003807121.1; XM_003807073.2.
DR AlphaFoldDB; A0A2R9A239; -.
DR Ensembl; ENSPPAT00000033997.1; ENSPPAP00000011342.1; ENSPPAG00000028875.1.
DR GeneID; 100971043; -.
DR KEGG; pps:100971043; -.
DR CTD; 84449; -.
DR GeneTree; ENSGT00940000163161; -.
DR OMA; ISDTCPE; -.
DR OrthoDB; 5254879at2759; -.
DR Proteomes; UP000240080; Chromosome 19.
DR Bgee; ENSPPAG00000028875; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 2.
DR Gene3D; 6.10.140.140; -; 2.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 11.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF137; ZINC FINGER PROTEIN 8; 1.
DR Pfam; PF01352; KRAB; 2.
DR Pfam; PF00096; zf-C2H2; 8.
DR Pfam; PF13465; zf-H2C2_2; 1.
DR SMART; SM00349; KRAB; 2.
DR SMART; SM00614; ZnF_BED; 2.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 7.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 2.
DR PROSITE; PS50805; KRAB; 2.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 10.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 11.
PE 4: Predicted;
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 4..74
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 203..274
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 338..365
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 366..393
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 394..421
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 422..449
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 450..477
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 478..505
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 506..533
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 534..561
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 562..589
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 590..617
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 618..645
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 665 AA; 75475 MW; 255421B0085C8887 CRC64;
MESVTFEDVA VEFIQEWALL DSARRSLCKY RMLDQCRTLA SRGTPPCKPS CVSQLGQRAE
PKATERGILH ATGVAWESQL KPKELPSMQD LLEEASSRDM QMGPGLFLRM QLVPSIEERE
TPLIREDRPA LQEPPWSPGC TGLKAAVQIQ RVVIPVPTLG HRNPWVARDS AVPACDPAWL
QEDKVEEEAM APGLPTACSQ EPVTFADVAV VFTPEEWVFL DSTQRSLYRD VMLENYRNLA
SVADQLCKPN ALSYLEERGE QWTTDRGVLS DTCAEPQCQP QEAIPSQDTF TEILSIDVKG
EQPQPGEKLY KYNELEKPFN SIEPLFQYQR IHAGEASYEC QEIRNSFFQS AHLIVPEKIH
SGDKSYACNK CEKSFRYSSD LIRHEKTHTA EKCFDCQECG QAFKYSSNLR RHMRTHTGEK
PFECSQCGKT FTRNFNLILH QRNHTGEKPY ECKDCGKAFN QPSSLRSHVR THTGEKPFEC
SQCGKAFREH SSLKTHLRTH TREKPYECNQ CGKPFRTSTH LNVHKRIHTG EKLYECGTCG
QVLSRLSTLK SHMRTHTGEK PYVCQECGRA FSEPSSLRKH ARTHSGKKPY ACQECGRAFG
QSSHLIVHVR THSAGRPYQC NQCEKAFRHS SSLTVHKRTH VGRENIRNGS LPLSMSHPYC
GPLAN
//
