ID A0A2R9A5L9_PANPA Unreviewed; 438 AA.
AC A0A2R9A5L9;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=F-box and leucine rich repeat protein 20 {ECO:0000313|Ensembl:ENSPPAP00000010595.1};
GN Name=FBXL20 {ECO:0000313|Ensembl:ENSPPAP00000010595.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000010595.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000010595.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000010595.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02111299; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111300; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111301; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111302; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111303; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111304; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111305; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111306; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111307; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02111308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9A5L9; -.
DR SMR; A0A2R9A5L9; -.
DR STRING; 9597.ENSPPAP00000010595; -.
DR Ensembl; ENSPPAT00000033247.1; ENSPPAP00000010595.1; ENSPPAG00000028492.1.
DR GeneTree; ENSGT00940000153845; -.
DR OrthoDB; 1078060at2759; -.
DR Proteomes; UP000240080; Chromosome 17.
DR Bgee; ENSPPAG00000028492; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR GO; GO:0098793; C:presynapse; IEA:GOC.
DR GO; GO:0098685; C:Schaffer collateral - CA1 synapse; IEA:Ensembl.
DR GO; GO:0001662; P:behavioral fear response; IEA:Ensembl.
DR GO; GO:0099575; P:regulation of protein catabolic process at presynapse, modulating synaptic transmission; IEA:Ensembl.
DR GO; GO:2000300; P:regulation of synaptic vesicle exocytosis; IEA:Ensembl.
DR CDD; cd22115; F-box_FBXL2-like; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR13382:SF58; F-BOX AND LEUCINE RICH REPEAT PROTEIN 20; 1.
DR PANTHER; PTHR13382; MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF13516; LRR_6; 4.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00367; LRR_CC; 12.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 24..70
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
SQ SEQUENCE 438 AA; 48575 MW; 3B81918E4460ABC6 CRC64;
MAPSRDRLLH FGFKATMFSN SDEAVINKKL PKELLLRIFS FLDVVTLCRC AQVSRAWNVL
ALDGSNWQRI DLFDFQRDIE GRVVENISKR CGGFLRKLSL RGCLGVGDNA LRTFAQNCRN
IEVLNLNGCT KTTDATCTSL SKFCSKLRHL DLASCTSITN MSLKALSEGC PLLEQLNISW
CDQVTKDGIQ ALVRGCGGLK ALFLKGCTQL EDEALKYIGA HCPELVTLNL QTCLQITDEG
LITICRGCHK LQSLCASGCS NITDAILNAL GQNCPRLRIL EVARCSQLTD VGFTTLARNC
HELEKMDLEE CVQITDSTLI QLSIHCPRLQ VLSLSHCELI TDDGIRHLGN GACAHDQLEV
IELDNCPLIT DASLEHLKSC HSLERIELYD CQQITRAGIK RLRTHLPNIK VHAYFAPVTP
PPSVGGSRQR FCRCCIIL
//
