ID A0A2R9A7U2_PANPA Unreviewed; 761 AA.
AC A0A2R9A7U2;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Pleckstrin homology domain containing M3 {ECO:0000313|Ensembl:ENSPPAP00000011471.1};
GN Name=PLEKHM3 {ECO:0000313|Ensembl:ENSPPAP00000011471.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000011471.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000011471.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02071417; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071419; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071420; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071421; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071422; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071424; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071425; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02071426; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003820862.1; XM_003820814.1.
DR AlphaFoldDB; A0A2R9A7U2; -.
DR Ensembl; ENSPPAT00000034129.1; ENSPPAP00000011471.1; ENSPPAG00000028938.1.
DR GeneID; 100977367; -.
DR KEGG; pps:100977367; -.
DR CTD; 389072; -.
DR GeneTree; ENSGT00940000159743; -.
DR OMA; CELCHNG; -.
DR OrthoDB; 126314at2759; -.
DR Proteomes; UP000240080; Unplaced.
DR Bgee; ENSPPAG00000028938; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd14674; PH_PLEKHM3_1; 1.
DR CDD; cd13327; PH_PLEKHM3_2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR037812; PLEKHM3_PH_1.
DR InterPro; IPR025258; RH_dom.
DR PANTHER; PTHR12326; PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12326:SF10; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF13901; RH_dom; 1.
DR SMART; SM01175; DUF4206; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 361..456
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
SQ SEQUENCE 761 AA; 87163 MW; 032B5137BDAB32CA CRC64;
MEALEVDDIS PALEVTEEFF STLDSNLEKA VQQAEVYGIQ EVPELVGHEV LSNITDNGAM
RNVTSLGKGG MIWDHCKSRL LETKAQNVFP AKEQFMVQRG TTPDNLSWME QKEASTFNFF
NICQRRRDRP RSVNDLLDET STFKPGHARS RSDITQVDWR VVLKTTPLQQ QQQQQPLLQG
PHVTRPSFLL PSPNKIEDAQ GNTEHKQTFP NILKKGYLEI RKDHDSYWQS CYAELSPYNL
YFYSLDSSGN QNLYATYQLS HFQSISVLGN LEARMVDTVL YDNTQLQLKA ESPWEALDWG
QKLWEVVHAA VPGYMGRQNE LTISPGLGHH DDYTQNHGFQ KKTSGLLPPS PVLDSSKQYQ
NILKSGTLYR LTVQNNWKAF TFVLSRAYLM AFQPGKLDED PLLSYNVDVC LAVQMDNLDG
CDSCFQVIFP QDVLRLRAET RQRAQEWMEA LKIAANVARS SEQNLQVTLR NKPKDQMGGH
ELRKNKRQSV TTSFLSILTT LSLERGLTAQ SFKCAGCQRS IGLSNGKAKV CNYSGWYYCS
NCHVDDSFLI PARIVHNWDT SKYKVSKQAK EFLEYVYEEP LIDIQQENAM LYHHAEPLAA
VLRLRQRLKS LRAYLFSCRA AVAEDLRRRI FPREYLLQQI HLYSLADLQQ VIEGKLAPFL
GKVIKFATSH VYSCSLCSQK GFICEICNNG EILYPFEDIS TSRCESCGAV FHSECKEKSV
PCPRCVRREL QKKQKSFWQR LNMDESLEEA CTMFELSYQN T
//
