ID A0A2R9A7V6_PANPA Unreviewed; 250 AA.
AC A0A2R9A7V6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Nudix hydrolase 13 {ECO:0000313|Ensembl:ENSPPAP00000013358.1};
GN Name=NUDT13 {ECO:0000313|Ensembl:ENSPPAP00000013358.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000013358.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000013358.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000013358.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJFE02053930; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02053931; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9A7V6; -.
DR Ensembl; ENSPPAT00000036028.1; ENSPPAP00000013358.1; ENSPPAG00000029827.1.
DR GeneTree; ENSGT00940000158879; -.
DR Proteomes; UP000240080; Chromosome 10.
DR Bgee; ENSPPAG00000029827; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.90.79.20; -; 1.
DR InterPro; IPR015375; NADH_PPase-like_N.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR015376; Znr_NADH_PPase.
DR PANTHER; PTHR11383:SF3; NAD(P)H PYROPHOSPHATASE NUDT13, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11383; NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 13; 1.
DR Pfam; PF09296; NUDIX-like; 1.
DR Pfam; PF09297; zf-NADH-PPase; 1.
DR SUPFAM; SSF55811; Nudix; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 48..162
FT /note="NADH pyrophosphatase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09296"
FT DOMAIN 165..195
FT /note="Zinc ribbon NADH pyrophosphatase"
FT /evidence="ECO:0000259|Pfam:PF09297"
SQ SEQUENCE 250 AA; 28227 MW; 6B814639D065D88E CRC64;
MSLYCGIACR RKFFWCYRLL STYVTKTRYL FELKEDDDAC KKAQQTGAFY LFHSLAPLLQ
TSAHQYLAPR HSLLELERLL GKFGQDAQRI EDSVLIGCSE QQEAWFALDL GLDSSFSISA
SLHKPEMETE LKGSFIELRK ALFQLNARDA SLLSTAQALL RWHDAHQFCS RSGQPTKKNM
AGSKRVCPSN NIIYYPQMAP VVITLVSDGT RCLLARQSSF PKGMYSALAG FCDIDPGELE
RIRDSCLVQS
//
