ID   A0A2R9ACA4_PANPA        Unreviewed;       712 AA.
AC   A0A2R9ACA4;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Cytoplasmic polyadenylation element binding protein 4 {ECO:0000313|Ensembl:ENSPPAP00000014919.1};
GN   Name=CPEB4 {ECO:0000313|Ensembl:ENSPPAP00000014919.1};
OS   Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000014919.1, ECO:0000313|Proteomes:UP000240080};
RN   [1] {ECO:0000313|Ensembl:ENSPPAP00000014919.1, ECO:0000313|Proteomes:UP000240080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22722832; DOI=10.1038/nature11128;
RA   Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA   Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA   Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA   Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA   Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA   Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA   Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA   Paabo S.;
RT   "The bonobo genome compared with the chimpanzee and human genomes.";
RL   Nature 486:527-531(2012).
RN   [2] {ECO:0000313|Ensembl:ENSPPAP00000014919.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the RRM CPEB family.
CC       {ECO:0000256|ARBA:ARBA00010347}.
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DR   EMBL; AJFE02044993; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003814056.1; XM_003814008.3.
DR   AlphaFoldDB; A0A2R9ACA4; -.
DR   SMR; A0A2R9ACA4; -.
DR   Ensembl; ENSPPAT00000037607.1; ENSPPAP00000014919.1; ENSPPAG00000030599.1.
DR   GeneID; 100984532; -.
DR   CTD; 80315; -.
DR   GeneTree; ENSGT00940000154998; -.
DR   OrthoDB; 5395046at2759; -.
DR   Proteomes; UP000240080; Chromosome 5.
DR   Bgee; ENSPPAG00000030599; Expressed in cerebellum and 6 other cell types or tissues.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR   GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR   CDD; cd19757; Bbox1; 1.
DR   CDD; cd12724; RRM1_CPEB2_like; 1.
DR   CDD; cd12726; RRM2_CPEB2_like; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR   InterPro; IPR032296; CEBP_ZZ.
DR   InterPro; IPR038446; CEBP_ZZ_sf.
DR   InterPro; IPR034819; CPEB.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR   PANTHER; PTHR12566:SF2; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4; 1.
DR   Pfam; PF16366; CEBP_ZZ; 1.
DR   Pfam; PF16367; RRM_7; 1.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR   PROSITE; PS50102; RRM; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176}.
FT   DOMAIN          455..542
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          563..641
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   REGION          20..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          78..133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          218..328
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..101
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        234..248
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        269..301
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   712 AA;  78314 MW;  6F001427FE1FB724 CRC64;
     MGDYGFGVLV QSNTGNKSAF PVRFHPHLQP PHHHQNATPS PAAFINNNTA ANGSSAGSAW
     LFPAPATHNI QDEILGSEKA KSQQQEQQDP LEKQQLSPSP GQEAGILPET EKAKSEENQG
     DNSSENGNGK EKIRIESPVL TGFDYQEATG LGTSTQPLTS SASSLTGFSN WSAAIAPSSS
     TIINEDASFF HQGGVPAASA NNGALLFQNF PHHVSPGFGG SFSPQIGPLS QHHPHHPHFQ
     HHHSQHQQQR RSPASPHPPP FTHRNAAFNQ LPHLANNLNK PPSPWSSYQS PSPTPSSSWS
     PGGGGYGGWG GSQGRDHRRG LNGGITPLNS ISPLKKNFAS NHIQLQKYAR PSSAFAPKSW
     MEDSLNRADN IFPFPDRPRT FDMHSLESSL IDIMRAENDT IKARTYGRRR GQSSLFPMED
     GFLDDGRGDQ PLHSGLGSPH CFSHQNGERV ERYSRKVFVG GLPPDIDEDE ITASFRRFGP
     LIVDWPHKAE SKSYFPPKGY AFLLFQDESS VQALIDACIE EDGKLYLCVS SPTIKDKPVQ
     IRPWNLSDSD FVMDGSQPLD PRKTIFVGGV PRPLRAVELA MIMDRLYGGV CYAGIDTDPE
     LKYPKGAGRV AFSNQQSYIA AISARFVQLQ HGEIDKRVEV KPYVLDDQLC DECQGARCGG
     KFAPFFCANV TCLQYYCEYC WAAIHSRAGR EFHKPLVKEG GDRPRHISFR WN
//