ID A0A2R9AE51_PANPA Unreviewed; 94 AA.
AC A0A2R9AE51;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=TNF receptor superfamily member 12A {ECO:0008006|Google:ProtNLM};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000015581.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000015581.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000015581.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02011495; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9AE51; -.
DR SMR; A0A2R9AE51; -.
DR Ensembl; ENSPPAT00000038272.1; ENSPPAP00000015581.1; ENSPPAG00000030926.1.
DR GeneTree; ENSGT00910000147000; -.
DR Proteomes; UP000240080; Chromosome 16.
DR Bgee; ENSPPAG00000030926; Expressed in placenta and 6 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0043065; P:positive regulation of apoptotic process; IEA:InterPro.
DR InterPro; IPR022316; TNFR_12.
DR PANTHER; PTHR32037; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 12A; 1.
DR PANTHER; PTHR32037:SF2; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 12A; 1.
DR Pfam; PF12191; stn_TNFRSF12A; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..94
FT /note="TNF receptor superfamily member 12A"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015352761"
FT TRANSMEM 43..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 94 AA; 10191 MW; E3C52B1308DC768F CRC64;
MARGSLRRLL RLLVLGLWLA LLRSVAGEQA PGAAAPPAPF RLLWPILGGA LSLTFVLGLL
SGFLVWRRCR RREKFTTPIE ETGGEGCPAV ALIQ
//
