ID A0A2R9AET9_PANPA Unreviewed; 499 AA.
AC A0A2R9AET9;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Inositol 1,4,5-triphosphate receptor associated 2 {ECO:0008006|Google:ProtNLM};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000013912.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000013912.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000013912.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02101981; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02101982; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02101983; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02101984; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02101985; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008952552.1; XM_008954304.1.
DR RefSeq; XP_008952553.1; XM_008954305.2.
DR RefSeq; XP_008952554.1; XM_008954306.2.
DR RefSeq; XP_008952555.1; XM_008954307.1.
DR RefSeq; XP_008952556.1; XM_008954308.1.
DR AlphaFoldDB; A0A2R9AET9; -.
DR Ensembl; ENSPPAT00000036587.1; ENSPPAP00000013912.1; ENSPPAG00000030103.1.
DR GeneID; 100992156; -.
DR KEGG; pps:100992156; -.
DR CTD; 4033; -.
DR GeneTree; ENSGT00530000063722; -.
DR OrthoDB; 2911667at2759; -.
DR Proteomes; UP000240080; Chromosome 12.
DR Bgee; ENSPPAG00000030103; Expressed in adult mammalian kidney and 4 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR008677; MRVI1.
DR PANTHER; PTHR15352:SF3; INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 2-RELATED; 1.
DR PANTHER; PTHR15352; LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1; 1.
DR Pfam; PF05781; MRVI1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 440..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..408
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 499 AA; 56239 MW; D6AE0F7481463AF6 CRC64;
MNDDPSMEEN GVERVCSENL LQSREYSSLP LPRRTSSTDG TITSSDPGLE ILNMASCDLD
SNSLCKKEED TRSASPTIEA QGTSPARDNI AFQDSTSKDK TILNLEAKEE PETIEEHKKE
HASGDSVVSP LPVTTVKSVN LRQSENTSAN EKEVEAEFLR LSLGFKCDWF TLEKRVKLEE
RSRDLAEENL KKEITNCLKL LESLTPLCED DNQAQEIIKK LEKSIKFLSQ CAARVASRAE
MLGAINQESR VSKAVEVMIQ HVENLKRMYA KEHAELEELK QVLLQNERSF NPLEDDDDCQ
IKKRSASLNS KPSSLRRVTI ASLPRNIGNA GMVAGMENND RFSRRSSSWR ILGSKQSEHR
PSLPRFISTY SWADAEEEKC ELKTKDDSEP PGEETVERTR KPSLSEKKNN PSKWDVSSVY
DTIASWATNL KSSIRKANKA LWLSIAFIVL FAALMSFLTG QLFQKSVDAA PTQQEDSWMS
LEHILWPFTR LRHNGPPPV
//
