GenomeNet

Database: UniProt
Entry: A0A2R9AGS6_PANPA
LinkDB: A0A2R9AGS6_PANPA
Original site: A0A2R9AGS6_PANPA 
ID   A0A2R9AGS6_PANPA        Unreviewed;      3114 AA.
AC   A0A2R9AGS6;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   02-DEC-2020, entry version 16.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000014512};
GN   Name=CENPF {ECO:0000313|Ensembl:ENSPPAP00000014512};
OS   Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000014512, ECO:0000313|Proteomes:UP000240080};
RN   [1] {ECO:0000313|Ensembl:ENSPPAP00000014512, ECO:0000313|Proteomes:UP000240080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22722832; DOI=10.1038/nature11128;
RA   Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA   Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA   Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA   Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA   Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA   Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA   Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA   Paabo S.;
RT   "The bonobo genome compared with the chimpanzee and human genomes.";
RL   Nature 486:527-531(2012).
RN   [2] {ECO:0000313|Ensembl:ENSPPAP00000014512}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2018) to UniProtKB.
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DR   EMBL; AJFE02045549; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02045550; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02045551; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02045552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003814203.1; XM_003814155.2.
DR   Ensembl; ENSPPAT00000037199; ENSPPAP00000014512; ENSPPAG00000030416.
DR   GeneID; 100992856; -.
DR   KEGG; pps:100992856; -.
DR   CTD; 1063; -.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   Proteomes; UP000240080; Chromosome 1.
DR   GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1893..2035
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2131..2270
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2313..2452
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2970..3013
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          211..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1667..1690
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1715..1747
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2891..2979
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3024..3114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          280..384
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          386..413
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          418..501
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          523..615
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          623..650
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          658..685
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          725..745
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          832..873
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          899..989
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1029..1109
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1132..1159
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1196..1244
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1293..1320
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1549..1612
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1624..1646
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1790..1817
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1825..1845
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1890..1917
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1932..1966
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1970..1997
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2002..2050
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2058..2078
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2107..2278
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2293..2316
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2324..2467
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2475..2544
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2555..2603
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2611..2684
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2689..2716
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2718..2773
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2781..2825
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2836..2863
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2871..2891
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        2916..2953
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2962..2979
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3029..3080
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3114 AA;  357722 MW;  09EF2574801AEEA2 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
     EGTNLKRENQ RLMEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
     CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASQTLPQA TMNHRDIARH QASSSVFSWQ QEKTPSHLSS NSQRTPIRRD
     FSASYFSGEQ EVTPSRSTLQ IGKRDANSSF FDNSSSPHLL DQLKAQNQEL RNKINELELR
     LQGHEKEMKG QVNKFQELQL QLEKAKVELI EKEKVLNKCR DELVRTTAQY DQASTKYTAL
     EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECIQMKAR
     LTQELQQAKN MHNVLQAELD KLTSVKQQLE NNLEEFKQKL CRAEQAFQAS QIKENELRRS
     MEEMKKENNL LKSQSEQKAR EVCHLEAELK NIKQCLNQSQ NFAEEMKAKN TSQETMLRDL
     QEKINQQENS LTLEKLKLAV ADLEKQRDCS QDLLKKREHH IEQLNDKLSK TEKESKALLS
     ALELKKKEYE ELKEEKTLFS CWKSENEKLL TQMESEKENL QSKINHLETC LKTQQIKSHE
     YNERVRTLEM DRENLSVEIR NLHNVLDSKS VEVETQKLAY VELQQKAEFS DQKHQKEIEN
     MCLKTSQLTG QVEDLEHKLQ LLSNEIMDKD QCYQDLHAEY ESLRDLLKSK DASLVTNEDH
     QRSLLAFDQQ PAMHHSFANI IGEQGSMPSE RSECHLEADQ SPKNSAILQN RVDSLEFSLE
     SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSAHQNVVA
     ETLSALENKE KELQLLNDKL ETEQAEIQEL KKSNHLLEDS LKELQLLSET LSLEKKEMSS
     IISLNKREIE ELTQENGTLK EMNASLNQEK MNLIQKSESF ANYIDEREKS ISELSDQYKQ
     EKLILLQRCE ETGNAYEDLS QKYKAAQEKN SKLECLLNEC TSLCENRKNE LEQLKEAFAK
     EHQEFLTKLA FAEERNQNLM LELETVQQAL RSEMTDNQNN SKSEPGGLKQ EIMTLKEEQN
     KMQKEVNDLL QENEQLMKVM KTKHECQNLE SEPIRNSVKE RDSERNQCNF KPQMDLEVKE
     ISLDSYNAQL VQLEAMLRSK ELKLQESEKE KECLQHELQT IRGDLETSNL QDMQSQEISG
     LKDCEIDAEE KYISGPHELS TSQNDNAHLQ CSLQTTMNKL NELEKICEIL QAEKYELVTE
     LNDSRSECIT ATRKMAEEVG KLLNEVKILN DDSGLLHGEL VEDIPGGEFG EQPNEQHPVS
     LAPLDESNSY EHLTLSDKEV QMHFAELQEK FSSLQSEHKI LHDQHCQMSS KMSELQTYVD
     SLKAENLVLS TNLRNFQGDL VKEMQLGLEE GLVPSLSSSC VPDSSSLSSL GDSCFYRALL
     EQTGDMSLLS NLEGTVSANQ CSVDEVFCSS LQEENLTRKE TPSAPAKGVE ELESLCEVYR
     QSLEKLEEKM ESQGIMKNKE IQELEQLLSS ERQELDCLRK QYLSENEQWQ QKLTSVTLEM
     ESKLAAEKKQ TEQLSLELEV ARLQLQGLDL SSRSLLGIDT EDAIQGRNES CDISKEHTSE
     TTERTPKHDV HQICDKDAQQ DLNLDIEKIT ETGAVKSTGE CSGEQSPDTN YEPPGEDKTQ
     GSSECISELS FSGPNASVPM DFLGNQENIQ NLQLRVKETS NENLRLLHVI EDRDRKVESL
     LNEMKELDSK LHLQEVQLMT KIEACIELEK IVGELKKENS DLSEKLEYFS CDNQELLQRV
     ETSEGLNSDL EMHADKSSRE DIEDNVAKVN DSWKERFLDV ENELSRIRSE KANIEHQALY
     LEADLEIVQT EKLCLEKDNE NKQKVIVCLE EELSVVTSER NQLRGELDTM SKKTMELDQL
     SEKMKEKTRE LESHQSECLH CIQVAEAEVK EKTELLQTLS SDVSELLKDK THLQEKLQSL
     EKDSQALSLT KCELENQIAQ MNKEKELLVK ESESLQARLS ESDYEKLNVS KALEAALVEK
     GEFALRLSST QEEVHQLRRG IEKLRVRIEA DEKKQLHVAE ELKEREREND SLKDKVENLE
     RELQMSEENQ ELVILDAENS KAEVETLKTQ IEEMARSLKV FELDLVTLRS EKENLTKQIQ
     EKQGQLSELD KLLSSFKSLL EEKEQAEIQI KEESKTAVEM LQNQLKELNE AVAALCGDQE
     IMKATEQSLD PPIEEEHQLR NSIEKLRARL EADEKKQLCV LQQLKESEHH ADLLKGRVEN
     LERELEIART NQEHAAHEAE NSKGEVEALK AKIEGMTQSL RDLELDLVTI RSEKENLTNE
     LQKEQERISE LEIINASFEN ILQEKEQEKV EMKEKSSTAM EMLQTQLKEL NERVAALHND
     QEACKAKEQN LSSQVECLEL EKAQLLQGLD EAKNNYIVLQ SSVNGLIQEV EDGKQKLEKK
     DEEISRLKNQ IQDEEQLVSK LSQVEGEHQL WKEQNLELRN LTVELEQKIQ VLQSKNASLQ
     DTLEVLQSSY KNLENELELT KMDKMSFVEK VNKMTAKETE LQREMHEMAQ KTAELQEELS
     GEKNRLAGEL QLLLEEIKSS KDQLKELTLE NSELKKSLDC MHKDQVEKEG KVREEIAEYQ
     LRLHEAEKKH QALLLDTNKQ YEVEIQTYRE KLTSKEECLS SQKLEIDLLK SSKEELNNSL
     KATTQILEEL KKTKMDNLKY VNQLKKENER AQGKMKLLIK SCKQLEEEKE ILQKELSQLQ
     AAQEKQKTGT VMDTKVDELT TEIKELKETL EEKTKEADEY LDKYCSLLIS HEKLEKAKEM
     LETQVAHLCS QQSKQDSRGS PLLDPVVPGP SPIPSVTEKR LSSGQNKASG KRQRSSGIWE
     NGRGPTPATP ESFSKKSKKA VMSGIHPAED MEGTESEPEG LPEVVKKGFA DIPTGKTSPY
     ILRRTTMATR TSPRLAAQKL ALSPLSLGKE NLAESSKPTA GGSRSQKVKV AQQSPVDSGT
     ILREPTTKSV LVNNLPERSP TDSPREGLRV KRGRLVPSPK AGLESKGSEN CKVQ
//
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