ID A0A2R9AGS6_PANPA Unreviewed; 3114 AA.
AC A0A2R9AGS6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 02-DEC-2020, entry version 16.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000014512};
GN Name=CENPF {ECO:0000313|Ensembl:ENSPPAP00000014512};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000014512, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000014512, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000014512}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (APR-2018) to UniProtKB.
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DR EMBL; AJFE02045549; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02045550; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02045551; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02045552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003814203.1; XM_003814155.2.
DR Ensembl; ENSPPAT00000037199; ENSPPAP00000014512; ENSPPAG00000030416.
DR GeneID; 100992856; -.
DR KEGG; pps:100992856; -.
DR CTD; 1063; -.
DR GeneTree; ENSGT00730000111187; -.
DR OMA; YNAQLVQ; -.
DR Proteomes; UP000240080; Chromosome 1.
DR GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 3.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1893..2035
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2131..2270
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2313..2452
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2970..3013
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 211..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1667..1690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1715..1747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2891..2979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3024..3114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 280..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 386..413
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 418..501
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 523..615
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 623..650
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 658..685
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 725..745
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 832..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 899..989
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1029..1109
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1132..1159
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1196..1244
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1293..1320
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1549..1612
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1624..1646
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1790..1817
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1825..1845
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1890..1917
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1932..1966
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1970..1997
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2002..2050
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2058..2078
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2107..2278
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2293..2316
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2324..2467
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2475..2544
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2555..2603
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2611..2684
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2689..2716
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2718..2773
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2781..2825
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2836..2863
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2871..2891
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2916..2953
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2962..2979
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3029..3080
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3114 AA; 357722 MW; 09EF2574801AEEA2 CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVENEKT
EGTNLKRENQ RLMEICESLE KTKQKISHEL QVKESQVNFQ EGQLNSGKKQ IEKLEQELKR
CKSELERSQQ AAQSADVSLN PCNTPQKIFT TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQTLPQA TMNHRDIARH QASSSVFSWQ QEKTPSHLSS NSQRTPIRRD
FSASYFSGEQ EVTPSRSTLQ IGKRDANSSF FDNSSSPHLL DQLKAQNQEL RNKINELELR
LQGHEKEMKG QVNKFQELQL QLEKAKVELI EKEKVLNKCR DELVRTTAQY DQASTKYTAL
EQKLKKLTED LSCQRQNAES ARCSLEQKIK EKEKEFQEEL SRQQRSFQTL DQECIQMKAR
LTQELQQAKN MHNVLQAELD KLTSVKQQLE NNLEEFKQKL CRAEQAFQAS QIKENELRRS
MEEMKKENNL LKSQSEQKAR EVCHLEAELK NIKQCLNQSQ NFAEEMKAKN TSQETMLRDL
QEKINQQENS LTLEKLKLAV ADLEKQRDCS QDLLKKREHH IEQLNDKLSK TEKESKALLS
ALELKKKEYE ELKEEKTLFS CWKSENEKLL TQMESEKENL QSKINHLETC LKTQQIKSHE
YNERVRTLEM DRENLSVEIR NLHNVLDSKS VEVETQKLAY VELQQKAEFS DQKHQKEIEN
MCLKTSQLTG QVEDLEHKLQ LLSNEIMDKD QCYQDLHAEY ESLRDLLKSK DASLVTNEDH
QRSLLAFDQQ PAMHHSFANI IGEQGSMPSE RSECHLEADQ SPKNSAILQN RVDSLEFSLE
SQKQMNSDLQ KQCEELVQIK GEIEENLMKA EQMHQSFVAE TSQRISKLQE DTSAHQNVVA
ETLSALENKE KELQLLNDKL ETEQAEIQEL KKSNHLLEDS LKELQLLSET LSLEKKEMSS
IISLNKREIE ELTQENGTLK EMNASLNQEK MNLIQKSESF ANYIDEREKS ISELSDQYKQ
EKLILLQRCE ETGNAYEDLS QKYKAAQEKN SKLECLLNEC TSLCENRKNE LEQLKEAFAK
EHQEFLTKLA FAEERNQNLM LELETVQQAL RSEMTDNQNN SKSEPGGLKQ EIMTLKEEQN
KMQKEVNDLL QENEQLMKVM KTKHECQNLE SEPIRNSVKE RDSERNQCNF KPQMDLEVKE
ISLDSYNAQL VQLEAMLRSK ELKLQESEKE KECLQHELQT IRGDLETSNL QDMQSQEISG
LKDCEIDAEE KYISGPHELS TSQNDNAHLQ CSLQTTMNKL NELEKICEIL QAEKYELVTE
LNDSRSECIT ATRKMAEEVG KLLNEVKILN DDSGLLHGEL VEDIPGGEFG EQPNEQHPVS
LAPLDESNSY EHLTLSDKEV QMHFAELQEK FSSLQSEHKI LHDQHCQMSS KMSELQTYVD
SLKAENLVLS TNLRNFQGDL VKEMQLGLEE GLVPSLSSSC VPDSSSLSSL GDSCFYRALL
EQTGDMSLLS NLEGTVSANQ CSVDEVFCSS LQEENLTRKE TPSAPAKGVE ELESLCEVYR
QSLEKLEEKM ESQGIMKNKE IQELEQLLSS ERQELDCLRK QYLSENEQWQ QKLTSVTLEM
ESKLAAEKKQ TEQLSLELEV ARLQLQGLDL SSRSLLGIDT EDAIQGRNES CDISKEHTSE
TTERTPKHDV HQICDKDAQQ DLNLDIEKIT ETGAVKSTGE CSGEQSPDTN YEPPGEDKTQ
GSSECISELS FSGPNASVPM DFLGNQENIQ NLQLRVKETS NENLRLLHVI EDRDRKVESL
LNEMKELDSK LHLQEVQLMT KIEACIELEK IVGELKKENS DLSEKLEYFS CDNQELLQRV
ETSEGLNSDL EMHADKSSRE DIEDNVAKVN DSWKERFLDV ENELSRIRSE KANIEHQALY
LEADLEIVQT EKLCLEKDNE NKQKVIVCLE EELSVVTSER NQLRGELDTM SKKTMELDQL
SEKMKEKTRE LESHQSECLH CIQVAEAEVK EKTELLQTLS SDVSELLKDK THLQEKLQSL
EKDSQALSLT KCELENQIAQ MNKEKELLVK ESESLQARLS ESDYEKLNVS KALEAALVEK
GEFALRLSST QEEVHQLRRG IEKLRVRIEA DEKKQLHVAE ELKEREREND SLKDKVENLE
RELQMSEENQ ELVILDAENS KAEVETLKTQ IEEMARSLKV FELDLVTLRS EKENLTKQIQ
EKQGQLSELD KLLSSFKSLL EEKEQAEIQI KEESKTAVEM LQNQLKELNE AVAALCGDQE
IMKATEQSLD PPIEEEHQLR NSIEKLRARL EADEKKQLCV LQQLKESEHH ADLLKGRVEN
LERELEIART NQEHAAHEAE NSKGEVEALK AKIEGMTQSL RDLELDLVTI RSEKENLTNE
LQKEQERISE LEIINASFEN ILQEKEQEKV EMKEKSSTAM EMLQTQLKEL NERVAALHND
QEACKAKEQN LSSQVECLEL EKAQLLQGLD EAKNNYIVLQ SSVNGLIQEV EDGKQKLEKK
DEEISRLKNQ IQDEEQLVSK LSQVEGEHQL WKEQNLELRN LTVELEQKIQ VLQSKNASLQ
DTLEVLQSSY KNLENELELT KMDKMSFVEK VNKMTAKETE LQREMHEMAQ KTAELQEELS
GEKNRLAGEL QLLLEEIKSS KDQLKELTLE NSELKKSLDC MHKDQVEKEG KVREEIAEYQ
LRLHEAEKKH QALLLDTNKQ YEVEIQTYRE KLTSKEECLS SQKLEIDLLK SSKEELNNSL
KATTQILEEL KKTKMDNLKY VNQLKKENER AQGKMKLLIK SCKQLEEEKE ILQKELSQLQ
AAQEKQKTGT VMDTKVDELT TEIKELKETL EEKTKEADEY LDKYCSLLIS HEKLEKAKEM
LETQVAHLCS QQSKQDSRGS PLLDPVVPGP SPIPSVTEKR LSSGQNKASG KRQRSSGIWE
NGRGPTPATP ESFSKKSKKA VMSGIHPAED MEGTESEPEG LPEVVKKGFA DIPTGKTSPY
ILRRTTMATR TSPRLAAQKL ALSPLSLGKE NLAESSKPTA GGSRSQKVKV AQQSPVDSGT
ILREPTTKSV LVNNLPERSP TDSPREGLRV KRGRLVPSPK AGLESKGSEN CKVQ
//
