ID A0A2R9AKI7_PANPA Unreviewed; 607 AA.
AC A0A2R9AKI7;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cadherin 1 {ECO:0000313|Ensembl:ENSPPAP00000015528.1};
GN Name=CDH1 {ECO:0000313|Ensembl:ENSPPAP00000015528.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000015528.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000015528.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000015528.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02047321; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047322; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047323; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047324; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047327; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047329; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02047330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9AKI7; -.
DR Ensembl; ENSPPAT00000038218.1; ENSPPAP00000015528.1; ENSPPAG00000030865.1.
DR GeneTree; ENSGT00940000157175; -.
DR Proteomes; UP000240080; Chromosome 16.
DR Bgee; ENSPPAG00000030865; Expressed in placenta and 6 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd00031; CA_like; 1.
DR CDD; cd11304; Cadherin_repeat; 2.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR014868; Cadherin_pro_dom.
DR PANTHER; PTHR24027:SF319; CADHERIN-1; 1.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR Pfam; PF00028; Cadherin; 3.
DR Pfam; PF08758; Cadherin_pro; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 3.
DR SMART; SM01055; Cadherin_pro; 1.
DR SUPFAM; SSF49313; Cadherin-like; 5.
DR PROSITE; PS00232; CADHERIN_1; 2.
DR PROSITE; PS50268; CADHERIN_2; 3.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 148..230
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 231..343
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 344..533
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 607 AA; 67199 MW; 0B9428C808F8DD7D CRC64;
ILPFFFPPTC WAQRQPSPCQ RDMNFEDCTG RQRTAYFSLD TRFKVGTDGV ITVKRPLRFH
NPQIHFLVYA WDSTYRKFST KVTLNTVGHH HRPPPHQASV SGIQAELLTF PNSSPGLRRQ
KRDWVIPPIS CPENEKGPFP KNLVQIKSNK DKEGKVFYSI TGQGADTPPV GVFIIERETG
WLKVTEPLDR ERIATYTLFS HAVSSNGNAV EDPMEILITV TDQNDNKPEF TQEVFKGSVM
EGALPGTSVM EVTATDADDD VNTYNAAIAY TILSQDPELP DKNMFTINRN TGVISVVTTG
LDRESFPTYT LVVQAADLQG EGLSTTATAV ITVTDTNDNP PIFNPTTYKG QVPENEANVI
ITTLKVTDAD APNTPAWEAV YTILNDDGGQ FVVTTNPVNN DGILKTAKVC MVPGKMQKLA
SSQLFMPLSP GIFLEKRLSR FQLHVVCWSY SKSQSLSPFR YRIWRDTANW LEINPDTGAI
STRAELDRED LEHVKNSTYT ALIIATDNGS PVATGTGTLL LILSDVNDNA PIPEPRTIFF
CERNPKPQVI NIIDADLPPN TSPFTAELTH GATSQSVGIT GLSHRTRPDS TFLTSSQGVM
MLQFLRP
//
