ID A0A2R9AN63_PANPA Unreviewed; 547 AA.
AC A0A2R9AN63;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Keratin 84 {ECO:0000313|Ensembl:ENSPPAP00000018593.1};
GN Name=KRT84 {ECO:0000313|Ensembl:ENSPPAP00000018593.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000018593.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000018593.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000018593.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; AJFE02109901; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9AN63; -.
DR Ensembl; ENSPPAT00000041326.1; ENSPPAP00000018593.1; ENSPPAG00000032438.1.
DR GeneTree; ENSGT00940000162040; -.
DR OMA; EQKCARS; -.
DR Proteomes; UP000240080; Chromosome 12.
DR GO; GO:0005829; C:cytosol; IEA:UniProt.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF17; KERATIN, TYPE II CUTICULAR HB4; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 165..476
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 162..252
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 374..454
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 547 AA; 60190 MW; 82B3E709569054B4 CRC64;
MSCRSYRVSS GHRVGNFSSC SAMTPQNLNR FRANSVSCWS GPGFRGLGSF GSRSVITSGS
YSPRIAAVGS RPIHCGVRFG AGCGMGFGDG RGVGLGPRAD SCVGLGFGAG SGIGYGFGGP
GFGYRVAGVG VPAAPSITAV TVNKSLLTPL NLEIDPNAQR VKKDEKEQIK TLNNKFASFI
DKVRFLEQQN KLLETKWSFL QEQKCVRSNL EPLFESYISN LRRQLEVLVS DQARLQAERN
HLQDVLEGFK KKYEEEVVCR ANAENEFVAL KKDVDATFMN KSDLEANVDT LTQEIDFLKT
LYMEEIQLLQ SHISETSVIV KMDNSRDLNL DGIIAEVKAQ YEEVARRSRA DAEAWYQTKY
EEMQVTAGQH CDNLHNIRNE INELTRLIQR LKAETEHAKA QRAKLEAAVA EAEQQGEATL
SDAKCKLADL ECALQQAKQD MARQLREYQE LMNAKLGLDI EIATYRRLLE GEESRLCEGV
GPVNICKKLV FSSSHISLLF KLPLNSGSHW GQEASDMAGL ATTVRGPALC TLSPTTGNSL
VLRGTLP
//
