ID A0A2R9AQB4_PANPA Unreviewed; 596 AA.
AC A0A2R9AQB4;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=HAUS augmin like complex subunit 3 {ECO:0000313|Ensembl:ENSPPAP00000019561.1};
GN Name=HAUS3 {ECO:0000313|Ensembl:ENSPPAP00000019561.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000019561.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000019561.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000019561.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}.
CC -!- SIMILARITY: Belongs to the HAUS3 family.
CC {ECO:0000256|ARBA:ARBA00009645}.
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DR EMBL; AJFE02041160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9AQB4; -.
DR STRING; 9597.ENSPPAP00000019561; -.
DR Ensembl; ENSPPAT00000042329.1; ENSPPAP00000019561.1; ENSPPAG00000032988.1.
DR GeneTree; ENSGT00390000011904; -.
DR OMA; LEWFCGN; -.
DR Proteomes; UP000240080; Chromosome 4.
DR Bgee; ENSPPAG00000032988; Expressed in placenta and 6 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0070652; C:HAUS complex; IEA:Ensembl.
DR GO; GO:1990498; C:mitotic spindle microtubule; IEA:Ensembl.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007098; P:centrosome cycle; IEA:Ensembl.
DR GO; GO:0051225; P:spindle assembly; IEA:Ensembl.
DR InterPro; IPR026206; HAUS3.
DR InterPro; IPR032733; HAUS3_N.
DR PANTHER; PTHR19378; GOLGIN- RELATED; 1.
DR PANTHER; PTHR19378:SF0; HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3; 1.
DR Pfam; PF14932; HAUS-augmin3; 1.
DR PRINTS; PR02089; HAUSAUGMINL3.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 22..274
FT /note="HAUS augmin-like complex subunit 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14932"
FT COILED 300..327
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 388..415
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 461..488
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 596 AA; 68794 MW; 5AE29F10665981D4 CRC64;
CGNIKKIGYP KADNLNGEDF DWLFEGVEDE SFLKWFCGNV NEQNVLSERE LEAFSILQKS
GKPILEGAAL DEALKTCKTS DLKTPRLDDK ELEKLEDEVQ TLLKLKNLKI QRRNKCQLMA
SVTSHKSLRL NAKEEEATKK LKQSQGILNA VITKISNELQ ALTDEVTQLM MFFRHSNLGQ
GTNPLVFLSQ FSLEKYLSQE EQSTAALTLY TKKQFFQGIH EVVESSNEDN FQLLDIQTPS
ICDNQEILEE RRLEMARLQL AYICAQHQLI HLKASNSSMK SSIKWAEESL HSLTSKAVDK
ENLDAKISSL TSEIMKLEKE VTQIKDRSLP AVVRENAQLL NMPVVKGDFD LQIAKQDYYT
ARQELVLNQL IKQKASFELL QLSYEIELRK HRDIYRQLEN LVQELSQSNM MLYKQLEMLT
DPSVSQQINP RNTIDTKDYS THRLYQVLEG ENKKKELFLT HGNLEEVAEK LKQNISLVQD
QLAVSAQEHS FFLSKRNKDV DMLCDTLYQG GNQLLLSDQE LTEQFHQVES QLNKLNHLLT
DILADVKTKR KTLANNKLHQ MEREFYVYFL KDEDYLKDIV ENLETQSKIK AVSLED
//
