ID A0A2R9AWR1_PANPA Unreviewed; 247 AA.
AC A0A2R9AWR1;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Coenzyme Q10A {ECO:0000313|Ensembl:ENSPPAP00000021713.1};
GN Name=COQ10A {ECO:0000313|Ensembl:ENSPPAP00000021713.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000021713.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000021713.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000021713.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Required for the function of coenzyme Q in the respiratory
CC chain. May serve as a chaperone or may be involved in the transport of
CC Q6 from its site of synthesis to the catalytic sites of the respiratory
CC complexes. {ECO:0000256|ARBA:ARBA00024947}.
CC -!- SUBUNIT: Interacts with coenzyme Q. {ECO:0000256|ARBA:ARBA00011814}.
CC -!- SIMILARITY: Belongs to the COQ10 family.
CC {ECO:0000256|ARBA:ARBA00006885}.
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DR EMBL; AJFE02087793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9597.ENSPPAP00000021713; -.
DR Ensembl; ENSPPAT00000044516.1; ENSPPAP00000021713.1; ENSPPAG00000034058.1.
DR GeneTree; ENSGT00940000160056; -.
DR Proteomes; UP000240080; Chromosome 12.
DR Bgee; ENSPPAG00000034058; Expressed in heart and 6 other cell types or tissues.
DR GO; GO:0048039; F:ubiquinone binding; IEA:InterPro.
DR GO; GO:0045333; P:cellular respiration; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:InterPro.
DR CDD; cd07813; COQ10p_like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR044996; COQ10-like.
DR InterPro; IPR005031; COQ10_START.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR12901:SF8; COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG A, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12901; SPERM PROTEIN HOMOLOG; 1.
DR Pfam; PF03364; Polyketide_cyc; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 93..222
FT /note="Coenzyme Q-binding protein COQ10 START"
FT /evidence="ECO:0000259|Pfam:PF03364"
FT REGION 24..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..43
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 247 AA; 27882 MW; 51265D080584DA38 CRC64;
XXXXXXXXXX XXXXXXXERC CRLSLSPGAQ PAPPPGPLPP PRPMRFLTSC SLLLPRAAQI
LAAEAGLPSS RSFMGFAAPF TNKRKAYSER RIMGYSMQEM YEVVSNIQEY REFVPWCKKS
LVVSSRKGHL KAQLEVGFPP VMERYTSAVS MVKPHMVKAV CTDGKLFNHL ETIWRFSPGI
PAYPRTCTVD FSISFEFRSL LHSQLATMFF DEVVKQNVAA FERRAATKFG PETAIPRELM
FHEVHQT
//
