ID A0A2R9AZ11_PANPA Unreviewed; 1116 AA.
AC A0A2R9AZ11;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=ELKS/RAB6-interacting/CAST family member 1 {ECO:0000313|Ensembl:ENSPPAP00000022460.1};
GN Name=ERC1 {ECO:0000313|Ensembl:ENSPPAP00000022460.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000022460.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000022460.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000022460.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AJFE02069726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069727; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069728; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069729; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069730; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069731; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069732; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069733; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069734; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069735; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003820422.1; XM_003820374.3.
DR AlphaFoldDB; A0A2R9AZ11; -.
DR Ensembl; ENSPPAT00000045270.1; ENSPPAP00000022460.1; ENSPPAG00000034303.1.
DR GeneID; 100977589; -.
DR KEGG; pps:100977589; -.
DR CTD; 23085; -.
DR GeneTree; ENSGT00650000093320; -.
DR OrthoDB; 2880381at2759; -.
DR Proteomes; UP000240080; Chromosome 12.
DR Bgee; ENSPPAG00000034303; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0098793; C:presynapse; IEA:UniProt.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.5.2440; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR019323; ELKS/CAST.
DR InterPro; IPR037245; FIP-RBD_C_sf.
DR InterPro; IPR019018; Rab-bd_FIP-RBD.
DR PANTHER; PTHR18861; ELKS/RAB6-INTERACTING/CAST PROTEIN; 1.
DR PANTHER; PTHR18861:SF1; ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1; 1.
DR Pfam; PF10174; Cast; 3.
DR Pfam; PF09457; RBD-FIP; 1.
DR SUPFAM; SSF144270; Eferin C-derminal domain-like; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS51511; FIP_RBD; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 1046..1108
FT /note="FIP-RBD"
FT /evidence="ECO:0000259|PROSITE:PS51511"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 587..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 790..836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 151..178
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 215..280
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 31..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1116 AA; 128070 MW; DBD61FD181E858B5 CRC64;
MYGSARSVGK VEPSSQSPGR SPRLPRSPRL GHRRTNSTGG SSGSSVGGGS GKTLSMENIQ
SLNAAYATSG PMYLSDHENV GSETPKSTMT LGRSGGRLPY GVRMTAMGSS PNIASSGVAS
DTIAFGEHHL PPVSMASTVP HSLRQARDNT IMDLQTQLKE VLRENDLLRK DVEVKESKLS
SSMNSIKTFW SPELKKERAL RKDEASKITI WKEQYRVVQE ENQHMQMTIQ ALQDELRIQR
DLNQLFQQDS SSRTGEPCVA ELTEENFQRL HAEHERQAKE LFLLRKTLEE MELRIETQKQ
TLNARDESIK KLLEMLQSKG LSAKATEEDH ERTRRLAEAE MHVHHLESLL EQKEKENSML
REEMHRRFEN APDSAKTKAL QTVIEMKDSK ISSMERGLRD LEEEIQMLKS NGALSTEERE
EEMKQMEVYR SHSKFMKNKV EQLKEELSSK EAQWEELKKR AAGLQAEIGQ VKQELSRKDT
ELLALQTKLE TLTNQFSDSK QHIEVLKESL TAKEQRAAIL QTEVDALRLR LEEKETMLNK
KTKQIQDMAE EKGTQAGEIH DLKDMLDVKE RKVNVLQKKI ENLQEQLRDK EKQMSSLKER
VKSLQADTTN TDTALTTLEE ALAEKERTIE RLKEQRDRDE REKQEEIDNY KKDLKDLKEK
VSLLQGDLSE KEASLLDLKE HASSLASSGL KKDSRLKTLE IALEQKKEEC LKMESQLKKA
HEAALEARAS PEMSDRIQHL EREITRYKDE SSKAQAEVDR LLEILKEVEN EKNDKDKKIA
ELERQVKDQN KKVANLKHKE QVEKKKSAQM LEEARRREDN LNDSSQQLQD SLRKKDDRIE
ELEEALRESV QITAEREMVL AQEESARTNA EKQVEELLMA MEKVKQELES MKAKLSSTQQ
SLAEKETHLT NLRAERRKHL EEVLEMKQEA LLAAISEKDA NIALLELSSS KKKTQEEVAA
LKREKDRLVQ QLKQQTQNRM KLMADNYEDD HFKSSHSNQT NHKPSPDQII QPLLELDQNR
SKLKLYIGHL TALCHERDPL ILRGLTPPAS YNLDDDQAAW ENELQKMTQG QLQDELEKGE
RDNAELQEFA NAILQQIADH CPDILEQVVN ALEESS
//
