ID A0A2R9B521_PANPA Unreviewed; 413 AA.
AC A0A2R9B521;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Protein unc-93 homolog A {ECO:0000256|ARBA:ARBA00040854};
GN Name=UNC93A {ECO:0000313|Ensembl:ENSPPAP00000023273.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000023273.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000023273.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000023273.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the unc-93 family.
CC {ECO:0000256|ARBA:ARBA00009172}.
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DR EMBL; AJFE02069241; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02069242; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9B521; -.
DR Ensembl; ENSPPAT00000046095.1; ENSPPAP00000023273.1; ENSPPAG00000034812.1.
DR GeneTree; ENSGT00530000063359; -.
DR Proteomes; UP000240080; Chromosome 6.
DR Bgee; ENSPPAG00000034812; Expressed in liver and 1 other cell type or tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17406; MFS_unc93A_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR010291; Ion_channel_UNC-93.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR19444:SF13; PROTEIN UNC-93 HOMOLOG A; 1.
DR PANTHER; PTHR19444; UNC-93 RELATED; 1.
DR Pfam; PF05978; UNC-93; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 413 AA; 45461 MW; 708FBF443FDFF538 CRC64;
MDRSLRNVLV VSFGFLLLFT AYGGLQSLQS SLYSEEGLGV TALSTLYGGM LLSSMFLPPL
LIERLGCKGT IILSMCGYVA FSVGNFFASW YTLIPTSILL GLGAAPLWSA QCTYLTITGN
THAEKVGKRG KDMVNQYFGI FFLIFQSSGV WGNLISSLVF GQTPSQGSGV LAVLMIAAFL
QPIRDVQRES EGEKKSVPFW STLLSTFKLY RDKRLCLLIL LPLYSGLQQG FLSSEYTRSY
VTCTLGIQFV GYVMICFSAT DALCSVLYGK VSQYTGRAVL YVLGAVTHVS CMIALLLWRP
RADHLAVFFV FSGLWGVADA VWQTQNNALY GVLFEKSKEA AFANYRLWEA LGFVIAFGYS
TFLCVHVKLY ILLGVLSLTM VAYGLVECVE SKNPIRPHAP GQANQAEDEE IQM
//
