ID A0A2R9B831_PANPA Unreviewed; 474 AA.
AC A0A2R9B831;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=TBCC domain-containing protein 1 {ECO:0000256|ARBA:ARBA00017559};
GN Name=TBCCD1 {ECO:0000313|Ensembl:ENSPPAP00000025764.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000025764.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000025764.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000025764.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm,
CC cytoskeleton, spindle pole {ECO:0000256|ARBA:ARBA00004647}.
CC -!- SIMILARITY: Belongs to the TBCC family.
CC {ECO:0000256|ARBA:ARBA00008848}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJFE02018505; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008953968.1; XM_008955720.2.
DR AlphaFoldDB; A0A2R9B831; -.
DR Ensembl; ENSPPAT00000048594.1; ENSPPAP00000025764.1; ENSPPAG00000036008.1.
DR GeneTree; ENSGT00470000042284; -.
DR OrthoDB; 3019544at2759; -.
DR Proteomes; UP000240080; Chromosome 3.
DR Bgee; ENSPPAG00000036008; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR Gene3D; 2.160.20.70; -; 1.
DR InterPro; IPR017901; C-CAP_CF_C-like.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR036223; CAP_C_sf.
DR InterPro; IPR006599; CARP_motif.
DR InterPro; IPR039589; TBCC1.
DR InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR PANTHER; PTHR16052:SF0; TBCC DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16052; UNCHARACTERIZED; 1.
DR Pfam; PF07986; TBCC; 1.
DR SMART; SM00673; CARP; 1.
DR SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 290..420
FT /note="C-CAP/cofactor C-like"
FT /evidence="ECO:0000259|PROSITE:PS51329"
SQ SEQUENCE 474 AA; 54003 MW; 6C682BC5CFBE1F14 CRC64;
MDQSRVLLWV KAEPFIVGAL QVPPPSKFSL HYLRKISTYV QIRATEGAYP RLYWSTWRHI
ACGKLQLAKD LAWLYFEIFD SLSMKTPEER LEWSEVLSNC MSEEEVEKQR NQLSVDTLQF
LLFLYIQQLN KVSLRTSLIG EEWPSPRNRS QSPDLTEKSN CHNKNWNDYS HQAFVYDHLS
DLLELLLDPK QLTASFHSTH SSLVSREAVV ALSFLIEGTI SRARKIYPLH ELALWQPLHA
DSGFSKISKT FSFYKLETWL RSCLTGNPFG TSACLKSGKK LAWAHQVEGT TKRAKIACNT
HVAPRMHRLV VMSQVYKQTL AKSSDTLVGA HVKIHRCNES FIYLLSPLRS VTIEKCRNSI
FVLGPVGTTL HLHSCDNVKV IAICHRLSIS STTGDTTEIP GGLPSVYQKA LGQREQKIQI
WQKTVKEAHL TKDQRKQFQV LVENKFYEWL INTGHRQQLD SLVPPAAGSK QAAG
//
