ID A0A2R9BEQ9_PANPA Unreviewed; 1106 AA.
AC A0A2R9BEQ9;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=RP1 axonemal microtubule associated {ECO:0000313|Ensembl:ENSPPAP00000027672.1};
GN Name=RP1 {ECO:0000313|Ensembl:ENSPPAP00000027672.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000027672.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000027672.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000027672.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; AJFE02081374; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02081375; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02081376; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9BEQ9; -.
DR Ensembl; ENSPPAT00000050515.1; ENSPPAP00000027672.1; ENSPPAG00000036902.1.
DR GeneTree; ENSGT00940000154242; -.
DR OMA; HEYAFFC; -.
DR Proteomes; UP000240080; Chromosome 8.
DR Bgee; ENSPPAG00000036902; Expressed in adult mammalian kidney.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd17145; DCX1_RP1; 1.
DR CDD; cd17147; DCX2_RP1; 1.
DR CDD; cd01756; PLAT_repeat; 2.
DR Gene3D; 2.80.10.50; -; 2.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR Gene3D; 3.10.20.230; Doublecortin domain; 2.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 3.
DR InterPro; IPR003533; Doublecortin_dom.
DR InterPro; IPR036572; Doublecortin_dom_sf.
DR InterPro; IPR008996; IL1/FGF.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR PANTHER; PTHR45901:SF7; LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45901; PROTEIN CBG12474; 1.
DR Pfam; PF03607; DCX; 2.
DR Pfam; PF01477; PLAT; 4.
DR SMART; SM00537; DCX; 2.
DR SMART; SM00308; LH2; 3.
DR SUPFAM; SSF50353; Cytokine; 2.
DR SUPFAM; SSF89837; Doublecortin (DC); 2.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 4.
DR PROSITE; PS50309; DC; 2.
DR PROSITE; PS50095; PLAT; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 36..118
FT /note="Doublecortin"
FT /evidence="ECO:0000259|PROSITE:PS50309"
FT DOMAIN 154..233
FT /note="Doublecortin"
FT /evidence="ECO:0000259|PROSITE:PS50309"
FT DOMAIN 264..380
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 392..509
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 856..970
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 982..1099
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..840
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..828
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1106 AA; 123644 MW; 39B8A5DFC4E0035E CRC64;
MSDTPSTGFS IIHPTSSEGQ VPPPRHLSLT HPVVAKRISF YKSGDPQFGG VRVVVNPRSF
KSFDALLDNL SRKVPLPFGV RNISTPRGRH SITRLEELED GESYLCSHGR KVQPVDLDKA
RRRPRPWLSS RAISAHSPPH PVAVAAPGVP RPPRSLVVFR NGDPKTRRAV LLSRRVTQSF
EAFLQHLTEV MQRPVVKLYA TDGRRVPSLQ AVILSSGAVV AAGREPFKPG NYDIQKYLLP
ARLPGISQRV YPKGNAKSES RKSSNWKVFI ITSDLPDAGT SSQIYIILYG QHRSSAPIYL
YGTDGARFQV GHEDIFTITV GDIGALFKIR IGHTNSGPSP SWHCKEIQLH NMNSGKQFYV
PVQRWLARDQ EDGEICREFP LLSKGQPVLP VTIYEVNVAT GELWNAGTVA NVYISIHGEK
GDTGSRQLFR SKSSFNFLRG QTDTFFLEAV HLGDLCKIVI GHDGLGPGNG WFLDDVVIKD
PTTNYEYAFF CHRWLDQGED DCKIVRELYA RDNSIFSARQ KLELKRKETW TAESWKFTKG
NTLQFYNKLT GGFVRLHPDG TVDAIGEKTD KYGVFDVIFN KRNICIFQSH EMRHLSLALD
NGIVTGMVSC EATTELRVLY QPNRCALLES ALVPGHTVVF DRHGKIADAS SAGYANLSKE
FVIFVKGVFL NSAVVLLATS LCQALCLQPD GSCTGVGSQS EKSYWKVHKI SSGICMFESV
KNAQMYLRIK DGRCDGTGTG DVDCHFKIKK NLKNASISLE STKSPGLFVG LQSDGQAKPM
IYTKDENVCF YPQVIQFGRE NPMGMSATPS QEEEKIHESK KQKKIPPESE ARSPLPSSTA
KEIRHFQSSE TLLSEDEWKV LVLTGNTGTQ ANVTLWVYGD KGVTGPISLR KDSSEQLFLP
GHEDEFQVEI RNTGNIYKIR IGHDGTSEQP EWNLQRVTMQ HTKSKKILDF AANVWLSRIQ
ADGDVVCELP VVKGGQAIFP LVRYQVDVYT GQLKHAETES EVFLCLFGER GDSGLRQLYK
SNMQVKFQRG QIDKFQVAAV SLGKLQKVLL RCEASDKSQY WYCEQVIVRE PGTTSESIFA
CQRWLPFMSQ GIIHSEIELY LQGEDY
//
