ID A0A2R9BG77_PANPA Unreviewed; 400 AA.
AC A0A2R9BG77;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=PHD finger protein 24 {ECO:0000313|Ensembl:ENSPPAP00000027276.1};
GN Name=PHF24 {ECO:0000313|Ensembl:ENSPPAP00000027276.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000027276.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000027276.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000027276.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02104583; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02104584; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003829863.1; XM_003829815.2.
DR AlphaFoldDB; A0A2R9BG77; -.
DR Ensembl; ENSPPAT00000050116.1; ENSPPAP00000027276.1; ENSPPAG00000036703.1.
DR KEGG; pps:100980269; -.
DR GeneTree; ENSGT00390000002865; -.
DR OMA; KGHIEWQ; -.
DR OrthoDB; 2919099at2759; -.
DR Proteomes; UP000240080; Chromosome 9.
DR Bgee; ENSPPAG00000036703; Expressed in prefrontal cortex and 2 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IEA:Ensembl.
DR GO; GO:0007214; P:gamma-aminobutyric acid signaling pathway; IEA:Ensembl.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:Ensembl.
DR GO; GO:0032228; P:regulation of synaptic transmission, GABAergic; IEA:Ensembl.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR031946; KIAA1045_Zf_RING.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46453:SF4; PHD FINGER PROTEIN 24; 1.
DR PANTHER; PTHR46453; PROTEIN KINASE C-BINDING PROTEIN 1; 1.
DR Pfam; PF16744; zf-RING_15; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 126..198
FT /note="KIAA1045 RING finger"
FT /evidence="ECO:0000259|Pfam:PF16744"
FT REGION 28..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 76..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 45163 MW; 808B233E94865590 CRC64;
MGVLMSKRQT VEQVQKVSLA VSAFKDGLRD RPSIRRTGEL PGSRRGTVEG SVQEVEEEKE
AEAGTSVVQE ESSAGRAAWE RLRDGRGVEP EEFDRTSRFT PPAFIRPTRK LDDDKPPEIC
LEPREPVVND EMCDVCEVWT AESLFPCRVC TRVFHDGCLR RMGYIQGDSA AEVTEMAHTE
TGWSCHYCDN INLLLTEEEM YSLTETFQRC KVIPDCSLTL EDFLRYRHQA AKRGDRDRAL
SEEQEEQAAR QFAALDPEHR GHIEWPDFLS HESLLLLQQL RPQNSLLRLL TVKERERARA
AFLARGSGIT VSEAECRQAQ HSWFCKQFPE APSCSVSISH VGPIADSSPA SSSSKSQDKT
LLPTEQESRF VDWPTFLQEN VLYILAARPN SAAIHLKPPG
//
