ID A0A2R9BIM6_PANPA Unreviewed; 570 AA.
AC A0A2R9BIM6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=CD6 molecule {ECO:0000313|Ensembl:ENSPPAP00000029514.1};
GN Name=CD6 {ECO:0000313|Ensembl:ENSPPAP00000029514.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000029514.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000029514.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000029514.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJFE02092412; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02092413; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9BIM6; -.
DR Ensembl; ENSPPAT00000052363.1; ENSPPAP00000029514.1; ENSPPAG00000037744.1.
DR GeneTree; ENSGT00940000161029; -.
DR Proteomes; UP000240080; Chromosome 11.
DR Bgee; ENSPPAG00000037744; Expressed in liver and 5 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.250.10; SRCR-like domain; 3.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071:SF18; LCCL_LECTIN ADHESIVE-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 3.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 3.
DR SUPFAM; SSF56487; SRCR-like; 3.
DR PROSITE; PS00420; SRCR_1; 1.
DR PROSITE; PS50287; SRCR_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..570
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015319139"
FT TRANSMEM 368..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 45..125
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 130..229
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 234..330
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT REGION 474..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..511
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 521..558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 199..209
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 299..309
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 570 AA; 61968 MW; B504D454957F8A0B CRC64;
MWLFFEITGL LTAALSGHPS PAPPDQLNTS SAESELWEPG ERLPVRLTNG SSSCSGTVEV
RLEASWEPAC GALWDSRAAE AVCRQLNATL AGAPALLCSG AEWRLCEVVE HACRSDGRRA
RVTCAENRAL RLVDGGGACA GRVEMLEHGE WGSVCDDTWD LEDAHVVCRQ LGCGWGVQAL
PGLHFTPGRG PIHRDQVNCS GAEAYLWDCP GLPGQHYCGH KEDAGVVCSE HQSWRLTGGA
DRCEGQVEVH FRGVWNTVCD SEWYPSEAKV LCQSLGCGTA VERPKGLPHS LSGRMYYSCN
GEELTLSNCS WRFNNSNLCS QSLAARVLCS DSRSLHNLST PEVPASVQTV TIESSVTVKI
ENKESRELML LIPSIVLGIL LLGSLIFIAF ILLRIKGKYV FMLPIQVQAP PPEDSDSGSD
SDYEHYDFSA QPPVALTTFY NSQRHRVTDE EVQQSRFQMP PLEEGLEELH ASHIPTANPG
HCITDPPSLG PQYHPRSSSE SSTSSGEDYC NSPKSKPPPW NPQVFSSERS SFLEQPPSLE
LAGTQPAFSG SPSPQPDSTD NDDYDDIGAA
//
