ID A0A2R9BJ86_PANPA Unreviewed; 523 AA.
AC A0A2R9BJ86;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Ankyrin repeat and SOCS box containing 3 {ECO:0000313|Ensembl:ENSPPAP00000029423.1};
GN Name=ASB3 {ECO:0000313|Ensembl:ENSPPAP00000029423.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000029423.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000029423.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the ankyrin SOCS box (ASB) family.
CC {ECO:0000256|ARBA:ARBA00005949}.
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DR EMBL; AJFE02079181; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02079182; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02079183; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02079184; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02079185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02079186; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9BJ86; -.
DR STRING; 9597.ENSPPAP00000029423; -.
DR Ensembl; ENSPPAT00000052272.1; ENSPPAP00000029423.1; ENSPPAG00000037721.1.
DR GeneTree; ENSGT00940000159080; -.
DR OMA; DCRSPMC; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000240080; Unplaced.
DR Bgee; ENSPPAG00000037721; Expressed in placenta and 6 other cell types or tissues.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03722; SOCS_ASB3; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037329; ASB3_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24173; ANKYRIN REPEAT CONTAINING; 1.
DR PANTHER; PTHR24173:SF74; UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 10.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 14..46
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 83..115
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 116..148
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 150..182
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 183..215
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 216..248
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 446..509
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 523 AA; 58399 MW; 434C93240933D888 CRC64;
RLVKQMDFTE AYADTCSTVG LAAREGNVKV LRKLLKKGRS VDVADNRGWM PIHEAAYHNS
VECLQMLINA DSSENYIKMK TFEGFCALHL AASQGHWKIV QILLEAGADP NATTLEETTP
LFLAVENGQI DVLRLLLQHG ANVNGSHSMC GWNSLHQASF QENAEIIKLL LRKGANKECQ
DDFGITPLFV AAQYGKLESL SILISSGANV NCQALDKATP LFIAAQEGHT KCVELLLSSG
ADPDLYCNED SWQLPIHAAA QMGHTKILDL LIPLTNRACD TGRNKVSPVY SAVFGGHEDC
LEILLRNGYS PDAQACLVFG FSSPVCMAFQ KDCEFFGIVN ILLKYGAQIN ELHLAYCLKY
EKFSIFRYFL RKGCSLGPWN HIYEFVNHAI KAQAKYKEWL PHLLVAGFDP LILLCNSWID
SVSIDTLIFT LEFTNWKTLA PAVERMLSAR ASNAWILQQH IASVPSLTHL CRLEIRSSLK
SERLRSDSYI SQLPLPRSLH NYLLYEDVLR MYEVPELAAI QDG
//
