ID A0A2R9BK10_PANPA Unreviewed; 468 AA.
AC A0A2R9BK10;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zinc finger protein 766 {ECO:0000313|Ensembl:ENSPPAP00000027075.1};
GN Name=ZNF766 {ECO:0000313|Ensembl:ENSPPAP00000027075.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000027075.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000027075.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000027075.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02022396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02022397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02022398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02022399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02022400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008958034.1; XM_008959786.1.
DR AlphaFoldDB; A0A2R9BK10; -.
DR Ensembl; ENSPPAT00000049911.1; ENSPPAP00000027075.1; ENSPPAG00000036606.1.
DR GeneID; 103784270; -.
DR KEGG; pps:103784270; -.
DR CTD; 90321; -.
DR GeneTree; ENSGT00940000165090; -.
DR OMA; FREIREH; -.
DR OrthoDB; 4771736at2759; -.
DR Proteomes; UP000240080; Chromosome 19.
DR Bgee; ENSPPAG00000036606; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF147; KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 9.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 10.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 10.
PE 4: Predicted;
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 9..80
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 187..214
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 215..242
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 243..270
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 271..298
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 299..326
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 327..354
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 355..382
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 383..410
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 411..438
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 439..462
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 468 AA; 54533 MW; 07963AE958C459B3 CRC64;
MAQLRRGHLT FRDVAIEFSQ EEWKCLDPVQ KALYRDVMLE NYRNLVSLGI CLPDLSIISM
MKQRTEPWAV ENEMKVAKNP DRWEGIKDIN TGRSCAVRSK AGNKPITNQL GLTFHLPLPE
LEIFQGEGKI YECNQVQKFI SHSSSVLPLQ RIYSGVKTQI FNKHRNDFVD FPLLSQEQKA
HIRRKPYECN EQSKVFRVSS SLPNHQVIHT ADKPNRCHEC GKTVRDKSGL AEHWRIRTGE
KPYKCKECGK LFNRIAYLAR HEKVHTGESP YKCNECGKVF SRITYLVRHQ KIHTREKPHK
CNKCGKVYSS SSYLAQHWRI HTGEKLYKCN KCGKEFSGHS SLTTHLLIHT GEKPYKCKEC
DKAFRHKFSL TVHQRNHNGE KPYKCHECGK VFTQVSHLAR HQKIHTGEKP YKCNECGKVF
TQNSHLANHQ RIHTGEKPYK CHVCGKVFRH SSWFVQHQRS VHERVLTN
//
