ID A0A2R9BL80_PANPA Unreviewed; 142 AA.
AC A0A2R9BL80;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cystatin 8 {ECO:0000313|Ensembl:ENSPPAP00000029157.1};
GN Name=CST8 {ECO:0000313|Ensembl:ENSPPAP00000029157.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000029157.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000029157.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000029157.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJFE02103321; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003829417.1; XM_003829369.2.
DR RefSeq; XP_003829418.1; XM_003829370.2.
DR RefSeq; XP_008952982.1; XM_008954734.1.
DR AlphaFoldDB; A0A2R9BL80; -.
DR STRING; 9597.ENSPPAP00000029157; -.
DR Ensembl; ENSPPAT00000052005.1; ENSPPAP00000029157.1; ENSPPAG00000037606.1.
DR GeneID; 100995839; -.
DR KEGG; pps:100995839; -.
DR GeneTree; ENSGT00940000162294; -.
DR OMA; MKKQCVD; -.
DR OrthoDB; 4635329at2759; -.
DR Proteomes; UP000240080; Chromosome 20.
DR Bgee; ENSPPAG00000037606; Expressed in testis.
DR GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005576; C:extracellular region; IEA:Ensembl.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00042; CY; 1.
DR Gene3D; 3.10.450.10; -; 1.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR046350; Cystatin_sf.
DR PANTHER; PTHR47010:SF1; CYSTATIN-8; 1.
DR PANTHER; PTHR47010; CYSTATIN-8-RELATED; 1.
DR Pfam; PF00031; Cystatin; 1.
DR SMART; SM00043; CY; 1.
DR SUPFAM; SSF54403; Cystatin/monellin; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..142
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018761064"
FT DOMAIN 30..140
FT /note="Cystatin"
FT /evidence="ECO:0000259|SMART:SM00043"
SQ SEQUENCE 142 AA; 16164 MW; 91ABC329EF865F89 CRC64;
MPRCRCLSLI LLTIPLALVA RKDPKKNETG VLRKLKPVNA SNANVKQCLW FAMQEYNKES
EDKYVFLVVK TLQAQLQVTN LLEYLIDVEI ARSDCRKPLS TNEICAIQEN SKLKKKLSCS
FLVGALPWNG EFTVMEKKCE DA
//
