ID A0A2R9BN21_PANPA Unreviewed; 645 AA.
AC A0A2R9BN21;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000030779.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000030779.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000030779.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02022999; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02023000; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02023001; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9BN21; -.
DR Ensembl; ENSPPAT00000053643.1; ENSPPAP00000030779.1; ENSPPAG00000038243.1.
DR GeneTree; ENSGT00940000156051; -.
DR Proteomes; UP000240080; Chromosome 1.
DR Bgee; ENSPPAG00000038243; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd22478; KH-I_FUBP1_rpt1; 1.
DR CDD; cd22481; KH-I_FUBP1_rpt2; 1.
DR CDD; cd22484; KH-I_FUBP1_rpt3; 1.
DR CDD; cd22487; KH-I_FUBP1_rpt4; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 4.
DR InterPro; IPR015096; FUBP_C.
DR InterPro; IPR048249; KH-I_FUBP1_dom1.
DR InterPro; IPR048250; KH-I_FUBP1_dom2.
DR InterPro; IPR048251; KH-I_FUBP1_dom3.
DR InterPro; IPR048252; KH-I_FUBP1_dom4.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288:SF99; FAR UPSTREAM ELEMENT-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR Pfam; PF09005; DUF1897; 2.
DR Pfam; PF00013; KH_1; 4.
DR SMART; SM00322; KH; 4.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 4.
DR PROSITE; PS50084; KH_TYPE_1; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 100..170
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 185..257
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 275..345
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 376..449
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 46..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 549..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..506
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 645 AA; 67778 MW; A3BDB144CB0DF9A6 CRC64;
MADYSTVPPP SSGSAGGGGG GGGGGGVNDA FKDALQRARQ IAAKIGGDAG TSLNSNDYGY
GGQKRPLEDG DQPDAKKVAP QNDLSFIEGK WCFLLFLSRS VMTEEYKVPD GMVGFIIGRG
GEQISRIQQE SGCKIQIAPD SGGLPERSCM LTGTPESVQS AKRLLDQIVE KGRPAPGFHH
GDGPGNAVQE IMIPASKAGL VIGKGGETIK QLQERAGVKM VMIQDGPQNT GADKPLRITG
DPYKVQQAKE MVLELIRDQG GFREVRNEYG SRIGGNEGID VPIPRFAVGI VIGRNGEMIK
KIQNDAGVRI QFKPDDGTTP ERIAQITGPP DRCQHAAEII TDLLRSVQAG NPGGPGPGGR
GRGRGQGNWN MGPPGGLQEF NFIVPTGKTG LIIGKGGETI KSISQQSGAR IELQRNPPPN
ADPNMKLFTI RGTPQQIDYA RQLIEEKIGG PVNPLGPPVP HGPHGVPGPH GPPGPPGPGT
PMGPYNPAPY NPGPPGPAPH GPPAPYAPQG WGNAYPHWQQ QAPPDPAKAG TDPNSAAWAA
YYAHYYQQQA QPPPAAPAGA PTTTQTNGQG DQQNPAPAGQ VDYTKAWEEY YKKMGQAVPA
PTGAPPGGQP DYSAAWAEYY RQQAAYYAQT SPQGMPQHPP APQGQ
//
