ID A0A2R9BPG1_PANPA Unreviewed; 61 AA.
AC A0A2R9BPG1;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=CAMPATH-1 antigen {ECO:0000256|ARBA:ARBA00013286};
GN Name=CD52 {ECO:0000313|Ensembl:ENSPPAP00000028531.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000028531.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000028531.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000028531.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May play a role in carrying and orienting carbohydrate, as
CC well as having a more specific role. {ECO:0000256|ARBA:ARBA00002087}.
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DR EMBL; AJFE02029126; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003809496.1; XM_003809448.2.
DR AlphaFoldDB; A0A2R9BPG1; -.
DR STRING; 9597.ENSPPAP00000028531; -.
DR Ensembl; ENSPPAT00000051378.1; ENSPPAP00000028531.1; ENSPPAG00000037302.1.
DR GeneID; 100975607; -.
DR KEGG; pps:100975607; -.
DR CTD; 1043; -.
DR GeneTree; ENSGT00860000134004; -.
DR OMA; FANTLMC; -.
DR Proteomes; UP000240080; Chromosome 1.
DR Bgee; ENSPPAG00000037302; Expressed in liver and 5 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR InterPro; IPR026643; CAMPATH-1.
DR PANTHER; PTHR15029; CAMPATH-1 ANTIGEN; 1.
DR PANTHER; PTHR15029:SF0; CAMPATH-1 ANTIGEN; 1.
DR Pfam; PF15116; CD52; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..61
FT /note="CAMPATH-1 antigen"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015329839"
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 61 AA; 6632 MW; 4AE2A0566F462EA6 CRC64;
MKRFLFLLLT ISLLVMVQIQ TGLSGQNDTS QTSSPSASSN MSGGIFLFFV ANAIIHLFCF
S
//
