ID A0A2R9BUR5_PANPA Unreviewed; 592 AA.
AC A0A2R9BUR5;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Calcineurin binding protein 1 {ECO:0000313|Ensembl:ENSPPAP00000033191.1};
GN Name=CABIN1 {ECO:0000313|Ensembl:ENSPPAP00000033191.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000033191.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000033191.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000033191.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AJFE02034605; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02034606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02034607; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02034608; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02034609; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02034610; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9BUR5; -.
DR Ensembl; ENSPPAT00000056061.1; ENSPPAP00000033191.1; ENSPPAG00000039279.1.
DR GeneTree; ENSGT00390000008529; -.
DR Proteomes; UP000240080; Chromosome 22.
DR Bgee; ENSPPAG00000039279; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:InterPro.
DR CDD; cd13839; MEF2_binding; 1.
DR InterPro; IPR033053; Hir3/CABIN1.
DR InterPro; IPR015134; MEF2-bd.
DR PANTHER; PTHR15502; CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED; 1.
DR PANTHER; PTHR15502:SF7; CALCINEURIN-BINDING PROTEIN CABIN-1; 1.
DR Pfam; PF09047; MEF2_binding; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 528..562
FT /note="Calcineurin-binding protein cabin-1 MEF2-binding"
FT /evidence="ECO:0000259|Pfam:PF09047"
FT REGION 93..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 570..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..181
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..592
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 592 AA; 63418 MW; DC1E607EE4A6A879 CRC64;
MPRRSRRGIW RIPVDEIDRP GSFAWHMNRS IVLLLKVLAQ LRDHSTLLKV SSMLQRTPDQ
GKKYLRDADR QVLAQRAFIL TVKVLEDTLS ELAEGSERPG PKVCGLPGAR MTTDVSHKAS
PEDGQEGLPQ PKKPPLADGS GPGPEPGGKV GLLNHRPVAM DAGDSADQSG ERKDKESPRA
GPTEPMDTSE ATVCHSDLEQ TPPLLPGRPA RDRGPESRPT ELSLEELSIS ARQQPTPLTP
AQPASAPAPA PATTTGTRAG GHPEEPLSRL SRKRKLLEDT ESGKTLLLDA YRVWQQGQKG
VAYDLGRVER IMSETYMLIK QVDEEAALEQ AVKFCQVHLG AAAQRQASGD TPTTPKHPKD
SRENFFPVTV VPTAPDPVPA DSVQRPSDAH TKPRPALAAA TTSITCPPSA SASTLDQSKD
PGPPRPHRPE ATPSMASLGP EGKLRPEPRR DGEAQEAASE TQPLSSPSTA ASSKAPSSGS
AQPPEGHPGK PEPSRAKSRP LPNMPKLVIP SAATKFPPEI TVTPPTPTLL SPKGSISEET
KQKLKSAILS AQSAANVRKE SLCQPALEVL ETSSQESSLE SETDEDDDYM DI
//
