ID A0A2R9BX04_PANPA Unreviewed; 368 AA.
AC A0A2R9BX04;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Fc gamma receptor Ia {ECO:0000313|Ensembl:ENSPPAP00000033996.1};
GN Name=FCGR1A {ECO:0000313|Ensembl:ENSPPAP00000033996.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000033996.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000033996.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000033996.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02026514; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9BX04; -.
DR STRING; 9597.ENSPPAP00000033996; -.
DR Ensembl; ENSPPAT00000056877.1; ENSPPAP00000033996.1; ENSPPAG00000039866.1.
DR GeneTree; ENSGT01050000244808; -.
DR Proteomes; UP000240080; Chromosome 1.
DR Bgee; ENSPPAG00000039866; Expressed in placenta and 3 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0019771; F:high-affinity IgG receptor activity; IEA:Ensembl.
DR GO; GO:0001788; P:antibody-dependent cellular cytotoxicity; IEA:Ensembl.
DR CDD; cd05752; Ig1_FcgammaR_like; 1.
DR CDD; cd05753; Ig2_FcgammaR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11481:SF11; HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I-RELATED; 1.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..368
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015308490"
FT TRANSMEM 283..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..80
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 89..178
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 184..271
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 346..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 368 AA; 42032 MW; 2A8C2ADB455D873C CRC64;
MWFLTTLLLW VDTTKAVITL QPPWVSVFQE ETVTLHCEVL HLPGSSSTQW FLNGTATQTS
TPSYRITSAS VNDSGEYRCQ RGLSGRSDPI QLEIHRGWLL LQVSSRVFTE GEPLALRCHA
WKDKPVYNVL YYRNGKAFKF FHWNSNLTIL KTNISHNGTY HCSGMGKHHY TSAGISVTVK
ELFPAPVLNA SVTSPLLEGN LVTLSCETKL LLQRPGLQLY FSFYMGSKTL RGRNTSSEYQ
ILTARREDSG LYWCEAATED GNVLKRSPEL ELQVLGLQLP TPVWFHVLFY LAVGIMFLVN
TVLWVTIRKE LKRKKKWNLE ISLDSGHEKK VISSLQEDRH LEEELKCQEQ KEEQLQEGMH
RKEPQGAT
//
