ID A0A2R9C0P8_PANPA Unreviewed; 246 AA.
AC A0A2R9C0P8;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000035493.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000035493.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000035493.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CREC family.
CC {ECO:0000256|ARBA:ARBA00006431}.
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DR EMBL; AJFE02107114; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02107115; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02107116; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02107117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02107118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02107119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02107120; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02107121; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02107122; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9C0P8; -.
DR Ensembl; ENSPPAT00000058382.1; ENSPPAP00000035493.1; ENSPPAG00000040558.1.
DR GeneTree; ENSGT01010000222360; -.
DR Proteomes; UP000240080; Chromosome 11.
DR Bgee; ENSPPAG00000040558; Expressed in placenta and 6 other cell types or tissues.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR10827; RETICULOCALBIN; 1.
DR PANTHER; PTHR10827:SF17; RETICULOCALBIN-1; 1.
DR Pfam; PF13202; EF-hand_5; 2.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 4.
DR PROSITE; PS50222; EF_HAND_2; 4.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 1..29
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 30..65
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 81..116
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 118..153
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 246 AA; 29352 MW; 8F6A638139F3329F CRC64;
KIVDRIDNDG DGFVTTEELK TWIKRVQKRY IFDNVAKVWK DYDRDKDDKI SWEEYKQATY
GYYLGNPAEF HDSSDHHTFK KMLPRDERRF KAADLNGDLT ATREEFTAFL HPEEFEHMKE
IVVLETLEDI DKNGDGFVDQ DEYIADMFSH EENGPEPDWV LSEREQFNEF RDLNKDGKLD
KDEIRHWILP QDYDHAQAEA RHLVYESDKN KDEKLTKEEI LENWNMFVGS QATNYGEDLT
KNHDEL
//
