ID A0A2R9C2H3_PANPA Unreviewed; 237 AA.
AC A0A2R9C2H3;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Intersectin 1 {ECO:0000313|Ensembl:ENSPPAP00000035942.1};
GN Name=ITSN1 {ECO:0000313|Ensembl:ENSPPAP00000035942.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000035942.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000035942.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000035942.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02084457; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084458; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084459; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084460; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084461; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02084464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9C2H3; -.
DR SMR; A0A2R9C2H3; -.
DR Ensembl; ENSPPAT00000058831.1; ENSPPAP00000035942.1; ENSPPAG00000040351.1.
DR GeneTree; ENSGT00940000157065; -.
DR Proteomes; UP000240080; Chromosome 21.
DR Bgee; ENSPPAG00000040351; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00052; EH; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR000261; EH_dom.
DR PANTHER; PTHR11216; EH DOMAIN; 1.
DR PANTHER; PTHR11216:SF68; INTERSECTIN-1; 1.
DR Pfam; PF12763; EF-hand_4; 1.
DR SMART; SM00027; EH; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50031; EH; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 105..194
FT /note="EH"
FT /evidence="ECO:0000259|PROSITE:PS50031"
FT DOMAIN 138..173
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 237 AA; 25104 MW; 63A5FF0BC9B31C96 CRC64;
MGGIASMPPL TAVAPVPMGS IPVVGMSPTL VSSVPTAAVP PLANGAPPVI QPLPAFAHPA
ATLPKSSSFS RSGPGSQLNT KLQKAQSFDV ASVPPVAEWA VPQSSRLKYR QLFNSHDKTM
SGHLTGPQAR TILMQSSLPQ AQLASIWNLS DIDQDGKLTA EEFILAMHLI DVAMSGQPLP
PVLPPEYIPP SFRRVRSGSG ISVISSTSVD QRLPEEPVLE DEQQQLEKKL PVAVFLV
//
