ID A0A2R9C7B2_PANPA Unreviewed; 308 AA.
AC A0A2R9C7B2;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Translocase of outer mitochondrial membrane 40 like {ECO:0000313|Ensembl:ENSPPAP00000037679.1};
GN Name=TOMM40L {ECO:0000313|Ensembl:ENSPPAP00000037679.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000037679.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000037679.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000037679.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004374}.
CC -!- SIMILARITY: Belongs to the Tom40 family.
CC {ECO:0000256|ARBA:ARBA00010510}.
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DR EMBL; AJFE02037532; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003811874.1; XM_003811826.2.
DR RefSeq; XP_008962460.1; XM_008964212.1.
DR AlphaFoldDB; A0A2R9C7B2; -.
DR SMR; A0A2R9C7B2; -.
DR STRING; 9597.ENSPPAP00000037679; -.
DR Ensembl; ENSPPAT00000060580.1; ENSPPAP00000037679.1; ENSPPAG00000041575.1.
DR GeneID; 100975843; -.
DR KEGG; pps:100975843; -.
DR CTD; 84134; -.
DR GeneTree; ENSGT00390000003308; -.
DR OMA; HRNCKDV; -.
DR OrthoDB; 5489886at2759; -.
DR Proteomes; UP000240080; Chromosome 1.
DR Bgee; ENSPPAG00000041575; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030150; P:protein import into mitochondrial matrix; IEA:InterPro.
DR CDD; cd07305; Porin3_Tom40; 1.
DR Gene3D; 2.40.160.10; Porin; 1.
DR InterPro; IPR023614; Porin_dom_sf.
DR InterPro; IPR027246; Porin_Euk/Tom40.
DR InterPro; IPR037930; Tom40.
DR PANTHER; PTHR10802; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40; 1.
DR PANTHER; PTHR10802:SF0; MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40B; 1.
DR Pfam; PF01459; Porin_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 308 AA; 33917 MW; B4347CD0610434D3 CRC64;
MGNTLGLAPM GTLPRRSPRR EEPLPNPGSF DELHRLCKDV FPAQMEGVKL VVNKVLSSHF
QVAHTIHMSA LGLPGYHLHA AYAGDWQLSP TEVFPTVVGD MDSSGSLNAQ VLLLLAERLR
AKAVFQTQQA KFLTWQFDGE YRGDDYTATL TLGNPDLIGE SVIMVAHFLQ SLTHRLVLGG
ELVYHRRPGE EGAILTLAGK YSAVHWVATL NVGSGGAHAS YYHRANEQVQ VGVEFEANTR
LQDTTFSFGY HLTLPQANMV FRGLVDSNWC VGAVLEKKMP PLPVTLALGA FLNHWRNRFH
CGFSITVG
//
