ID A0A2R9C8Y6_PANPA Unreviewed; 1339 AA.
AC A0A2R9C8Y6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Apoptotic chromatin condensation inducer 1 {ECO:0000313|Ensembl:ENSPPAP00000037403.1};
GN Name=ACIN1 {ECO:0000313|Ensembl:ENSPPAP00000037403.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000037403.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000037403.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000037403.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02024213; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02024214; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02024215; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02024216; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003808146.1; XM_003808098.2.
DR STRING; 9597.ENSPPAP00000037403; -.
DR Ensembl; ENSPPAT00000060303.1; ENSPPAP00000037403.1; ENSPPAG00000041392.1.
DR GeneID; 100982806; -.
DR KEGG; pps:100982806; -.
DR CTD; 22985; -.
DR GeneTree; ENSGT00710000106790; -.
DR OMA; DYHKGIR; -.
DR OrthoDB; 1411884at2759; -.
DR Proteomes; UP000240080; Chromosome 14.
DR Bgee; ENSPPAG00000041392; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd12432; RRM_ACINU; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR034257; Acinus_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR032552; RSB_motif.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR46589; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR PANTHER; PTHR46589:SF1; APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS; 1.
DR Pfam; PF16294; RSB_motif; 1.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 72..106
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..863
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 890..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1096..1339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..234
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..289
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..398
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 642..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..736
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..780
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 798..817
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 890..913
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1096..1110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1128
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1130..1175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1176..1190
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1191..1214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1234..1320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1339 AA; 151782 MW; 211135E2B7838C4E CRC64;
MWRRKHPRTS GGTRGVLSGN RGVEYGSGRG HLGTFEGRWR KLPKMPEAVG TDPSTSRKMA
ELEEVTLDGK PLQALRVTDL KAALEQRGLA KSGQKSALVK RLKGALMLEN LQKHSTPHAA
FQPNSQIGEE MSQNSFIKQY LEKQQELLRQ RLEREAREAA ELEEASAESE DEMIHPEGVA
SLLPPDFQSS LERPELELSR HSPRKSSSIS EEKGDSDDEK PRKGERRSSR VRQARAAKLS
EGSQPAEEEE DQETPSRNLR VRADRNLKTE EEEEEEEEDD EEEEDDDEGQ KSREAPILKE
FKEEGEEMPR VKPEEMMDER PKTRSQEQEV LERGGRFTRS QEEARKSHLA RQQQEKEMKT
TSPLEEEERE IKSSQGLKEK SKSPSPPRLT EDRKKTSLVA LPEQTASEEE TPPPLLTKEA
SSPPHPQLHS EEEIEPMEGP APPVLIQLSP PNTDTDTREL LVSQHTVQLV GGLSPLSSPS
DTKAESPAEK VPEESVLPLV QKSTLADYSA QKDLEPESDR SAQPLPLKIE ELALAKGITE
ECLKQPSLEQ KEGRRASHTL LPSHRLKQSA DSSSSRSSSS SSSSSRSRSR SPDSSGSRSH
SPLRSKQRDV AQARTHANPR GRPKMGSRST SESRSRSRSR SRSRSASSNS RKSLSPGVSR
DSSTSYTETK DPSSGQEVAT PPVPQLQVCE PKERTSTSSS SVQARRLSQP ESAEKHVTQR
LQPERGSPKK CEAEEAEPPA ATQPQTSETQ TSHLPESERI HHTVEEKEEV TMDTSENRPE
NDVPEPPMPI ADQVSNDDRP EGSVEDEEKK ESSLPKSFKR KISVVSATKG VPAGNSDTEG
GQPGRKRRWG ASTATTQKKP SISITTESLK SLIPDIKPLA GQEAVVDLHA DDSRISEDET
ERNGDDGTHD KGLKICRTVT QVVPAEGQEN GQREEEEEEK EPEAEPPVPP QVSVEVALPP
PAEHEVKKVT LGDTLTRRSI SQQKSGVSIT IDDPVRTAQV PSPPRGKISN IVHISNLVRP
FTLGQLKELL GRTGTLVEEA FWIDKIKSHC FVTYSTVEEA VATRTALHGV KWPQSNPKFL
CADYAEQDEL DYHRGLLVDR PSETKTEEQG IPRPLHPPPP PPVQPPQHPR AEQREQERAV
REQWAERERE MERRERTRSE REWDRDKVRE GPRSRSRSRD RRRKERAKSK EKKSEKKEKA
QEEPPAKLLD DLFRKTKAAP CIYWLPLTDS QIVQKEAERA ERAKEREKRR KEQEEEEQKE
REKEAERERN RQLEREKRRE HSRERDRERE RERERDRGDR DRDRERDRER GRERDRRDTK
RHSRSRSRST PVRDRGGRR
//
