ID A0A2R9CCP6_PANPA Unreviewed; 708 AA.
AC A0A2R9CCP6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Tetratricopeptide repeat domain 12 {ECO:0000313|Ensembl:ENSPPAP00000039644.1};
GN Name=TTC12 {ECO:0000313|Ensembl:ENSPPAP00000039644.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000039644.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000039644.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000039644.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02014429; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02014430; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2R9CCP6; -.
DR STRING; 9597.ENSPPAP00000039644; -.
DR Ensembl; ENSPPAT00000062555.1; ENSPPAP00000039644.1; ENSPPAG00000042509.1.
DR GeneTree; ENSGT00940000161758; -.
DR Proteomes; UP000240080; Chromosome 11.
DR Bgee; ENSPPAG00000042509; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0070286; P:axonemal dynein complex assembly; IEA:Ensembl.
DR GO; GO:0007288; P:sperm axoneme assembly; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR043195; TTC12.
DR PANTHER; PTHR46540; TETRATRICOPEPTIDE REPEAT PROTEIN 12; 1.
DR PANTHER; PTHR46540:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 12; 1.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 177..210
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 708 AA; 78718 MW; 815B12D3D6A7F687 CRC64;
GDAGQELGIQ KAVTSLSNLI QEMNSDDPVV QQKAVLETEK RLLLMEEDQE EDECRTTLNK
TMISPPQTAM KSAEEINSEA FLASVEKDAK ERAKRRRENK VLADALKEKG NEAFAEGNYE
TAILRYSEGL EKLKDMKVLY TNRAQAYMKL EDYEKALVDC EWALKSFSFM QCDEKCTKAY
FHMGKANLAL KNYSVSRECY KKILEINPKL QTQVKDYLNQ VDLQEKADLQ EKEAHELLDS
GKNTAVTTKN LLETLSKPDQ IPLFYAGGIE ILTEMINECT EQTLFRTHNG FSIISDNEVI
RRCFSTAGND AVEEMVCVSV LKLWQAVCSG NEENQRVLVM HHDRARLLAA LLSSEVLAIR
QQSFALLLQL AQTESGRSLI INHLDLTRLL EALVSFLDFS DKEANTAMGL FTDLALEERF
QVWFQANLPG VLPALTGVLK TDPKVSSSSA LCQCITVMGN LSAEPTTRRH MAACEEFGDG
CLSLLARCEE DVDLFREVIY TLLGLMMNLC LQAPFVSEVW AVEVSRRCLS LLNSQDGGIL
TRAAGVLSRT LSSSLKIVEE ALRAGVVKKM MKFLKTGGET ASRYAIKILA ICTNSYHEAR
EEVIRLDKKL SVMMKLLSSE DEVLVGNAAL CLGNCMEVPN VASSLLKTDV LQVLLKLAGS
DTQKTAVQVN AGIALGKLCT AEPRFAAQLR KLHGLEILNS TMKYVSDS
//
