ID A0A2R9CE71_PANPA Unreviewed; 406 AA.
AC A0A2R9CE71;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Endoplasmic reticulum protein 44 {ECO:0000313|Ensembl:ENSPPAP00000036612.1};
GN Name=ERP44 {ECO:0000313|Ensembl:ENSPPAP00000036612.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000036612.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000036612.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000036612.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AJFE02070729; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02070730; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02070731; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02070732; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02070733; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02070734; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003820684.1; XM_003820636.2.
DR AlphaFoldDB; A0A2R9CE71; -.
DR SMR; A0A2R9CE71; -.
DR STRING; 9597.ENSPPAP00000036612; -.
DR Ensembl; ENSPPAT00000059504.1; ENSPPAP00000036612.1; ENSPPAG00000041063.1.
DR GeneID; 100988047; -.
DR KEGG; pps:100988047; -.
DR CTD; 23071; -.
DR GeneTree; ENSGT00930000151031; -.
DR OMA; DWCRFSN; -.
DR OrthoDB; 90290at2759; -.
DR Proteomes; UP000240080; Chromosome 9.
DR Bgee; ENSPPAG00000041063; Expressed in placenta and 6 other cell types or tissues.
DR GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:Ensembl.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR GO; GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:Ensembl.
DR GO; GO:0003756; F:protein disulfide isomerase activity; IEA:Ensembl.
DR GO; GO:0009100; P:glycoprotein metabolic process; IEA:Ensembl.
DR GO; GO:0006457; P:protein folding; IEA:Ensembl.
DR GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
DR GO; GO:0006986; P:response to unfolded protein; IEA:Ensembl.
DR CDD; cd02996; PDI_a_ERp44; 1.
DR CDD; cd03072; PDI_b'_ERp44; 1.
DR CDD; cd03070; PDI_b_ERp44; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 3.
DR InterPro; IPR041862; ERp44_PDI_b.
DR InterPro; IPR041870; ERp44_PDI_b.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46295; ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44; 1.
DR PANTHER; PTHR46295:SF1; ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 3.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..406
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015325969"
FT DOMAIN 18..141
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 360..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 406 AA; 46971 MW; 3865DCF3811BC263 CRC64;
MHPAVFLSLP DLRCSLLLLV TWVFTPVTTE ITSLDTENID EILNNADVAL VNFYADWCRF
SQMLHPIFEE ASDVIKEEFP NENQVVFARV DCDQHSDIAQ RYRISKYPTL KLFRNGMMMK
REYRGQRSVK ALADYIRQQK SDPIQEIRDL AEITTLDRSK RNIIGYFEQK DSDNYRVFER
VANILHDDCA FLSAFGDVSK PERYSGDNII YKPPGHSAPD MVYLGAMTNF DVTYNWIQDK
CVPLVREITF ENGEELTEEG LPFLILFHMK EDTESLEIFQ NEVARQLISE KGTINFLHAD
CDKFRHPLLH IQKTPADCPV IAIDSFRHMY VFGDFKDVLI PGKLKQFVFD LHSGKLHREF
HHGPDPTDTA PGEQAQDVAS SPPESSFQKL APSEYRYTLL RDRDEL
//
