ID A0A2R9CGF6_PANPA Unreviewed; 2358 AA.
AC A0A2R9CGF6;
DT 20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT 20-JUN-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Jumonji domain containing 1C {ECO:0000313|Ensembl:ENSPPAP00000041040.1};
GN Name=JMJD1C {ECO:0000313|Ensembl:ENSPPAP00000041040.1};
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000041040.1, ECO:0000313|Proteomes:UP000240080};
RN [1] {ECO:0000313|Ensembl:ENSPPAP00000041040.1, ECO:0000313|Proteomes:UP000240080}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22722832; DOI=10.1038/nature11128;
RA Prufer K., Munch K., Hellmann I., Akagi K., Miller J.R., Walenz B.,
RA Koren S., Sutton G., Kodira C., Winer R., Knight J.R., Mullikin J.C.,
RA Meader S.J., Ponting C.P., Lunter G., Higashino S., Hobolth A., Dutheil J.,
RA Karakoc E., Alkan C., Sajjadian S., Catacchio C.R., Ventura M.,
RA Marques-Bonet T., Eichler E.E., Andre C., Atencia R., Mugisha L.,
RA Junhold J., Patterson N., Siebauer M., Good J.M., Fischer A., Ptak S.E.,
RA Lachmann M., Symer D.E., Mailund T., Schierup M.H., Andres A.M., Kelso J.,
RA Paabo S.;
RT "The bonobo genome compared with the chimpanzee and human genomes.";
RL Nature 486:527-531(2012).
RN [2] {ECO:0000313|Ensembl:ENSPPAP00000041040.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AJFE02106831; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106832; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106833; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106834; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106835; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106836; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106837; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106838; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106839; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AJFE02106840; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003830359.1; XM_003830311.2.
DR RefSeq; XP_014201941.1; XM_014346455.1.
DR Ensembl; ENSPPAT00000063961.1; ENSPPAP00000041040.1; ENSPPAG00000043117.1.
DR GeneID; 100988552; -.
DR KEGG; pps:100988552; -.
DR CTD; 221037; -.
DR GeneTree; ENSGT00940000158210; -.
DR OrthoDB; 3473445at2759; -.
DR Proteomes; UP000240080; Chromosome 10.
DR Bgee; ENSPPAG00000043117; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IEA:InterPro.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR045109; JHDM2-like.
DR InterPro; IPR003347; JmjC_dom.
DR PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR PANTHER; PTHR12549:SF6; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 2C-RELATED; 1.
DR Pfam; PF02373; JmjC; 1.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT DOMAIN 2092..2316
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 96..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1060..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1432..1510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1789..1882
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..274
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..296
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1432..1501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1789..1823
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1833..1864
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1865..1882
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2358 AA; 263073 MW; 2A009ADC424FF20F CRC64;
MQGPYSLNGY RVRVYRQDSA TQWFTGIITH HDLFTRTMIV MNDQVLEPQN VDPSMVQMTF
LDDVVHSLLK GENIGITSRR RSRANQNVNA VHSHYTRAQA NSPRPAMNSQ AAVPKQNTHQ
QQQQRSIRPN KRKGSDSSIP DEEKMKEEKY DYISRGENPK GKNKHLMNKR RKPEEDEKKL
NMKRLRTDNV SDFSESSDSE NSNKRIIDNS SEQKPENELK NKNTSKINGE EGKPHNNEKA
GEETLKDSQP PWDQIQEDKK HEEAEKRKSV DTQLQEDMII HSSEQSTVSD HNSNDLLPQE
CNMDKTHTME LLPKEKFVSR PPTPKCVIDI TNDTNLEKVA QENSSTFGLQ TLQKMDPNVS
DSKHSIANAK FLETAKQDSD QSWVSDVVKV DLTQSGVTNA SSGNDHLNME KEKYVSYISP
LSAVSVMEDK LHKRSPPPET IKSKLNTSVD THKIKSSPSP EVVKPKITHS PDSVKSKATY
VNSQATGERR LANKIEHELS RCSFHPIPTR SSTLETTKSP LIIDKNEHFT VYRDPALIGS
ETGANHISPF LSQHPFPLHS SSHRTCLNPG THHPALTPAP HLLAGSSSQT PLPTINTHPL
TSGPHHAVHH PHLLPTVLPG VPTASLLGGH PRLESAHASS LSHLALAHQQ QQQLLQHQSP
HLLGQAHPSA SYNQLGLYPI IWQYPNGTHA YSGLGLPSSK WVHPENAVNA EASLRRNSPS
PWLHQPTPVT SADGIGLLSH IPVRPSSAEP HRPLKITAHS SPPLTKTLVD HHKEELERKA
FMEPLRSVAS TSAKNDLDLN RSQTGKDCHL HRHFVDPVLN QLQRPPQETG ERLNKYKEEH
RRILQESIDV APFTTKIKGV EGERENYSRV ASSSSSPKSH IIKQDMDVER SVSDLYKMKH
SVPQSLPQSN YFTTLSNSVV NEPPRSYPSK EVSNIYGDKQ SNALAAAAAN PQTLTSFITS
LSKPPPLIKH QPESEGLVGK IPEHLPHQIA SHSVTTFRND CRSPTHLTVS STNTLRSMPA
LHRAPVFHPP IHHSLERKEG SYSSLSPPTL TPVMPVNAGG KVQESQKPPT LIPEPKDSQA
NFKSSSEQSL TEMWRPNNNL SKEKTEWHVE KSSGKLQAAM ASVIVRPSSS TKTDSMPAMQ
LASKDRVSER SSAGAHKTDC LKLAEAGETG RIILPNVNSD SVHTKSEKNF QAVSQGSVPS
SVMSAVNTMC NTKTDVITSA ADTTSVSSWG GSEVISSLSN TILASTSSEC VSSKSVSQPV
AQKQECKVST TAPVTLASSK TGSVVQPSSG FSGTTDFIHL KKHKAALAAA QYKSSNASET
EPNAIKNQTL SASLPLDSTV ICSTINKANS VGNGQASQTS QPNYHTKLKK AWLTRHSEED
KNTNKMENSG NSVSEIIKPC SVNLIASTSS DIQNSVDSKI IVDKYVKDDK VNRRKAKRTY
ESGSESGDSD ESESKSEQRT KRQPKPTYKK KQNDLQKRKG EIEEDLKPNG VLSRSAKERS
KLKLQSSSNT GIPRSVLKDW RKVKKLKQTG ESFLQDDSCC EIGPNLQKCR ECRLIRSKKG
EEPAHSPVFC RFYYFRRLSF SKNGVVRIDG FSSPDQYDDE AMSLWTHENF EDDELDVETS
KYILDIIGDK FCQLVTSEKT ALSWVKKDAK IAWKRAVRGV REMCDACEAT LFNIHWVCQK
CGFVVCLDCY KAKERKSSRD KELYAWMKCV KGQPHDHKHL MPTQIIPGSV LTDLLDAMHT
LREKYGIKSH CHCTNKQNLQ VGNFPTMNGV SQVLQNVLNH SNKISLCMPE SQQQNTPPKS
EKNGGSSPES DVGTDNKLTP PESQSPLHWL ADLAEQKARE EKKENKELTL ENQIKEEREQ
DNSESPNGRT SPLVSQNNEQ GSTLRDLLTT TAGKLRVGST DAGIAFAPVY SMGAPSSKSG
RTMPNILDDI IASVVENKIP PSKTSKINVK PELKEEPEES IISAVDENNK LYSDIPHSWI
CEKHILWLKD YKNSSNWKLF KECWKQGQPA VVSGVHKKMN ISLWKAESIS LDFGDHQADL
LNCKDSIISN ANVKEFWDGF EEVSKRQKNK SGETVVLKLK DWPSGEDFKT MMPARYEDLL
KSLPLPEYCN PEGKFNLASH LPGFFVRPDL GPRLCSAYGV VAAKDHDIGT TNLHIEVSDV
VNILVYVGIA KGNGILSKAG ILKKFEEEDL DDILRKRLKD SSEIPGALWH IYAGKDVDKI
REFLQKISKE QGLEVLPEHD PIRDQSWYVN KKLRQRLLEE YGVRTCTLIQ FLGDAIVLPA
GALHQVQNFH SCIQVTEDFV SPEHLVESFH LTQELRLLKE EINYDDKLQV KNILYHAVKE
MVRALKIHED EVEDMEEN
//
