UniProt: A0A2R9CS43

Database: UniProt
Entry: A0A2R9CS43_PANPA

LinkDB:  A0A2R9CS43_PANPA 
Original site:  A0A2R9CS43_PANPA

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Ontology (21)   
   GO (21)   
Gene (5)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
   ENSEMBL-UP (3)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (10)   
   EMBL (10)   
Protein domain (6)   
   InterPro (3)   
   Pfam (2)   
   PROSITE (1)   
All databases (43)   

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ID   A0A2R9CS43_PANPA        Unreviewed;       190 AA.
AC   A0A2R9CS43;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=COMM domain-containing protein 1 {ECO:0000256|ARBA:ARBA00016551};
GN   Name=COMMD1 {ECO:0000313|Ensembl:ENSPPAP00000041952.1};
OS   Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9597 {ECO:0000313|Ensembl:ENSPPAP00000041952.1, ECO:0000313|Proteomes:UP000240080};
RN   [1] {ECO:0000313|Ensembl:ENSPPAP00000041952.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AJFE02109203; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109204; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109205; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109206; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109207; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109208; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109209; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109210; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AJFE02109212; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003830923.1; XM_003830875.2.
DR   AlphaFoldDB; A0A2R9CS43; -.
DR   STRING; 9597.ENSPPAP00000041952; -.
DR   Ensembl; ENSPPAT00000064880.1; ENSPPAP00000041952.1; ENSPPAG00000043574.1.
DR   GeneID; 100972929; -.
DR   KEGG; pps:100972929; -.
DR   CTD; 150684; -.
DR   GeneTree; ENSGT00390000012029; -.
DR   OMA; WRIDGKS; -.
DR   OrthoDB; 6795at2759; -.
DR   Proteomes; UP000240080; Unplaced.
DR   Bgee; ENSPPAG00000043574; Expressed in placenta and 6 other cell types or tissues.
DR   GO; GO:0031462; C:Cul2-RING ubiquitin ligase complex; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005769; C:early endosome; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0055037; C:recycling endosome; IEA:Ensembl.
DR   GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR   GO; GO:0070300; F:phosphatidic acid binding; IEA:Ensembl.
DR   GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0019871; F:sodium channel inhibitor activity; IEA:Ensembl.
DR   GO; GO:0055070; P:copper ion homeostasis; IEA:Ensembl.
DR   GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:Ensembl.
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; IEA:Ensembl.
DR   GO; GO:1902306; P:negative regulation of sodium ion transmembrane transport; IEA:Ensembl.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:Ensembl.
DR   GO; GO:0048227; P:plasma membrane to endosome transport; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   CDD; cd04749; Commd1_MURR1; 1.
DR   InterPro; IPR017920; COMM.
DR   InterPro; IPR033776; COMMD1_N.
DR   InterPro; IPR037351; Murr1.
DR   PANTHER; PTHR21199; COMM DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR21199:SF1; COMM DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF07258; COMM_domain; 1.
DR   Pfam; PF17221; COMMD1_N; 1.
DR   PROSITE; PS51269; COMM; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000240080}.
FT   DOMAIN          118..186
FT                   /note="COMM"
FT                   /evidence="ECO:0000259|PROSITE:PS51269"
SQ   SEQUENCE   190 AA;  21152 MW;  8C900791CB1C61DC CRC64;
     MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVAPEEFRP FLAKMRGILK
     SIASADMDFN QLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR
     GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE
     SISTLISQPN
//

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