ID A0A2S0HTG9_9FLAO Unreviewed; 272 AA.
AC A0A2S0HTG9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=3-deoxy-8-phosphooctulonate synthase {ECO:0000256|ARBA:ARBA00012693};
DE EC=2.5.1.55 {ECO:0000256|ARBA:ARBA00012693};
GN ORFNames=C5O00_01670 {ECO:0000313|EMBL:AVI49942.1};
OS Pukyongia salina.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Pukyongia.
OX NCBI_TaxID=2094025 {ECO:0000313|EMBL:AVI49942.1, ECO:0000313|Proteomes:UP000238442};
RN [1] {ECO:0000313|EMBL:AVI49942.1, ECO:0000313|Proteomes:UP000238442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RR4-38 {ECO:0000313|EMBL:AVI49942.1,
RC ECO:0000313|Proteomes:UP000238442};
RA Kim Y.-S., Jang Y.H., Kim K.-H.;
RT "Genomic analysis of the strain RR4-38 isolated from a seawater
RT recirculating aquaculture system.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-
CC alpha-D-manno-2-octulosonate-8-phosphate + phosphate;
CC Xref=Rhea:RHEA:14053, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:57693, ChEBI:CHEBI:58702, ChEBI:CHEBI:85985; EC=2.5.1.55;
CC Evidence={ECO:0000256|ARBA:ARBA00001069};
CC -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004756}.
CC -!- PATHWAY: Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate
CC biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate:
CC step 2/3. {ECO:0000256|ARBA:ARBA00004845}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the KdsA family.
CC {ECO:0000256|ARBA:ARBA00010499}.
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DR EMBL; CP027062; AVI49942.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S0HTG9; -.
DR KEGG; aue:C5O00_01670; -.
DR OrthoDB; 9776934at2; -.
DR UniPathway; UPA00030; -.
DR UniPathway; UPA00357; UER00474.
DR Proteomes; UP000238442; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006218; DAHP1/KDSA.
DR InterPro; IPR006269; KDO8P_synthase.
DR NCBIfam; TIGR01362; KDO8P_synth; 1.
DR PANTHER; PTHR21057:SF2; 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE 1-RELATED; 1.
DR PANTHER; PTHR21057; PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE; 1.
DR Pfam; PF00793; DAHP_synth_1; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000238442};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 8..260
FT /note="DAHP synthetase I/KDSA"
FT /evidence="ECO:0000259|Pfam:PF00793"
SQ SEQUENCE 272 AA; 29537 MW; A0CABC9A59BE9B43 CRC64;
MNLESIPKIK HTEANNFFLM AGPCAIEGEE MALLIAEKVV AITNRLNIPY IFKGSYKKAN
RSRIDSFTGI GDEKALEILK KVSEKFDIPT VTDIHESGDA AIAAQYVDVL QIPAFLVRQT
DLVVAAANTG KVVNLKKGQF MSPESMKHAV KKVTDCGNEK VLVTDRGTMF GYQDMVVDFR
GIPTMKSFAT TVLDVTHSLQ QPNQAAGVTG GRPEMISTIA RAGIATGVDG LFIETHFDPA
NAKSDGANML DLSLLEKLLS DLVAIRNTIN HL
//
