ID A0A2S0N5H5_9BURK Unreviewed; 723 AA.
AC A0A2S0N5H5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=C6571_14185 {ECO:0000313|EMBL:AVO43277.1};
OS Simplicispira suum.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Simplicispira.
OX NCBI_TaxID=2109915 {ECO:0000313|EMBL:AVO43277.1, ECO:0000313|Proteomes:UP000239326};
RN [1] {ECO:0000313|EMBL:AVO43277.1, ECO:0000313|Proteomes:UP000239326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC1-8 {ECO:0000313|EMBL:AVO43277.1,
RC ECO:0000313|Proteomes:UP000239326};
RA Kim S.-J., Heo J., Kwon S.-W.;
RT "Genome sequencing of Simplicispira sp.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP027669; AVO43277.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S0N5H5; -.
DR KEGG; simp:C6571_14185; -.
DR OrthoDB; 5389366at2; -.
DR Proteomes; UP000239326; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AVO43277.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:AVO43277.1}.
FT DOMAIN 352..575
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 603..719
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 654
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 723 AA; 78229 MW; 717E98AB2508E5D4 CRC64;
MTKPDLSYLL RKSDPSAYTD PPARPQQERR DEAARPVGPT AALIARLRNY QVELEAQNKV
LRYSQAAAES ASERFEALFS SVPLALMVID AHDMVVQANS MAHRSFQPTE ADRPLTSLLP
FVDAAHTPRV RHAFSLAAGS GHAEATEVVF HIGANAQING DLHIARIEAP QDDGPPQYQY
LCAIVDQGPL LAERRALQQS TWALQQRNEQ LYASEKRHAA VINSALDAIV CVDRTQRITV
FNPTAAALFQ CPESDALGSP LERFLPQAAQ ALAFAQVTTQ AMLGEMTART ASGRELAVEV
SVSFEQLADG GTTTVFARDL TAHKRAEARR GELELQLRES HKMQAVGTMA GGIAHDFNNI
LGAILGNVEL ARADCPADSP VQESLREISK AGRRARDLVR QILTFSRNEA PRRTPVPLAA
ILHDTERLLR VTLPPDIELR VRASASVPAV LADATQVEQA VLNLCTNAIQ AMSGRRGRVD
VEVQAAHPDA RTCERLGLTA GRYVSVTVRD SGPGMDPDTL TRVFEPFFTT KPVGQGTGLG
LAVVHGVMRA HGGAVDVGST PGKGSCFTLY FPAADDHVVP ADFAPSSPSP LADALESAGP
ERHVMYVDDD QALVFLVQRL LRRRGYKVSG FTDPREALSA LAQAPWEVDL LVTDYNMPGF
SGLELLREAR RLHPDLPMAL ASGYVTQEIE QAAMDAGAAA LVHKPNDVEE LCATVQRLVR
GDG
//
