ID   A0A2S0P6Q0_9NEIS        Unreviewed;      1418 AA.
AC   A0A2S0P6Q0;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Insecticide toxin TcdB middle/N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DAI18_02195 {ECO:0000313|EMBL:AVY92983.1};
OS   Microvirgula aerodenitrificans.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales;
OC   Aquaspirillaceae; Microvirgula.
OX   NCBI_TaxID=57480 {ECO:0000313|EMBL:AVY92983.1, ECO:0000313|Proteomes:UP000244173};
RN   [1] {ECO:0000313|EMBL:AVY92983.1, ECO:0000313|Proteomes:UP000244173}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BE2.4 {ECO:0000313|EMBL:AVY92983.1,
RC   ECO:0000313|Proteomes:UP000244173};
RA   Anderson E., Jang J., Ishii S.;
RT   "Denitrifier Microvirgula.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   EMBL; CP028519; AVY92983.1; -; Genomic_DNA.
DR   OrthoDB; 8596388at2; -.
DR   Proteomes; UP000244173; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR028994; Integrin_alpha_N.
DR   InterPro; IPR031325; RHS_repeat.
DR   InterPro; IPR003284; Sal_SpvB.
DR   InterPro; IPR022044; TcdB_toxin_mid/C.
DR   InterPro; IPR022045; TcdB_toxin_mid/N.
DR   Pfam; PF05593; RHS_repeat; 1.
DR   Pfam; PF03534; SpvB; 1.
DR   Pfam; PF12255; TcdB_toxin_midC; 1.
DR   Pfam; PF12256; TcdB_toxin_midN; 1.
DR   PRINTS; PR01341; SALSPVBPROT.
DR   SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000244173};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   DOMAIN          645..798
FT                   /note="Insecticide toxin TcdB middle/N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12256"
FT   DOMAIN          844..985
FT                   /note="Insecticide toxin TcdB middle/C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12255"
FT   REGION          1370..1418
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1378..1394
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1418 AA;  153839 MW;  F5D0CB28C842709B CRC64;
     MFSDSSSITI SLPSLPTIHD ALPGPGDGSG PTLSAGLVSF DIPLSLPVAR ESTPALTLGY
     SAGAGNGPCG TGWRLALPTI QRRTRLGVPQ YNDDDVFVGP DGEPLVPQLG ADGKVVVQTG
     VTRCVGSTLP LSYTVTPYSS RTQTDYSRYQ YWQSGTSAFW LWFERNGVIH CLGYTAQISD
     PASPGHIARW LIEESLFPNG EHVLYRYVAE DSAGISDSRD QTAQRYPDRI DYANLTASAT
     FFLFGTVPDE AGWLRTLKFD YGQRPADDQP PPAWDTSGVW TCRPDAFSDY RFGFELRCHR
     LCRQLLAFGR DPASPATPVL LSCLSFSYDS SPFGSQLSAL RRRAYEADGS LLDLPATLFS
     YSSSTPAVDG QYQPLSDWAE PPGYQLVDLY GDGLPGLLYQ QAGAWLYRAP QRVISADPDG
     ISYGKATALP QAPKAAAGGR QLLLDMTGDG RLDWVSVQPG LAGFFALNDD HSWRGFTPFS
     AFPAEFLQSG AQLANLVGDG RLDLVLIGPN GVRLYANTGS GFAAPVNVAC RNGPLPVPGR
     DARELVAFAD VLAAGSPQLL RVTFNQLTGW PDLGRGAFGA PLTFALDPLD EPAAFNPARL
     FLADVSGAGG VDLLYAKADG LRLYRNQAGN GFDSPLTLPW PDGFNYDDSA ELRFGDLAGH
     GAVSLLLSQR HGEPKHWRYD FLSGPAGLLS QIDNQCGRTI QLSYRSSAQF RLDEKRGDPA
     SVSHLPLTLA LCSQVIDRDA VQGHADTRRY AYQGGVYDPT ERTFNGFRRI DRSDLGDAYD
     GYGQPLVEPA LTRSWFHTGQ ADDATDRSDY YAGDAQAYTL GDTRVTSWDG SKDSTPTSSD
     PLWHQALKGK LLHEEVYPAD ISDAVPRRVS SSRWQLRVLQ TATAGADAVV SPLLLETLSA
     DYDDSGLDPR FSQSIILSRD GDGNITHQVR AHYPRRAQDP AFSDPLLTPG QLAATYDDSQ
     QRLRLQEETP GWTRVVDDSN WRLGLPTQQI EQALDYPASS AGSGLSFEIL SAPDGLLSPD
     APRTLTGWCT QSYLNASSVL LAIGRVTGQQ QALLDDSTAH SAYDPVLGSD QVATQLQAAG
     YVLQTLNKLN YWVAQRQSAS YADGSGFYRL QTLQASARTG ASTLSWDAAG CWLTGLTDAL
     GKQTTLGYDA RFWRPARLTD VNGQWHEVRY DALGRVMAAS HSGFDPVASY LPGGLTPEQA
     SVSASDALQG MAEVVIYAAG SWIGEIDSRL PAHRLVLSAD RVSTDPARQI RQRMDYRDGH
     DRAWRTVQLV EPGDGYRLSE NGDFVYDESG EAVSGPLTVR WQVAAGDECS AGGLALLQYS
     GYCVDRSRPA REAPPLPFAQ QYRDATLKPV LTQRGDGNYR LQRPCPWYVV GQDENDSYQG
     ESEPEPEPDP EPEPDSDGLQ APAGNGDTRP EIGMWGNV
//