ID   A0A2S0U8U0_9BACL        Unreviewed;      1003 AA.
AC   A0A2S0U8U0;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:AWB44219.1};
GN   ORFNames=DCC85_08330 {ECO:0000313|EMBL:AWB44219.1};
OS   Paenibacillus sp. CAA11.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1532905 {ECO:0000313|EMBL:AWB44219.1, ECO:0000313|Proteomes:UP000244407};
RN   [1] {ECO:0000313|EMBL:AWB44219.1, ECO:0000313|Proteomes:UP000244407}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CAA11 {ECO:0000313|EMBL:AWB44219.1,
RC   ECO:0000313|Proteomes:UP000244407};
RA   Um Y., Kim S., Gong G.;
RT   "Complete genome of CAA11.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; CP028922; AWB44219.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S0U8U0; -.
DR   OrthoDB; 9772207at2; -.
DR   Proteomes; UP000244407; Chromosome.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244407}.
FT   DOMAIN          501..579
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1003 AA;  114258 MW;  A8BC711DFD2BED5D CRC64;
     MPYPKIRLER LKSWKLDIEE RIYSPIAELQ VEAWVTSEPV LYVNRKAGRR VELKPGERWG
     ELWDCAWFHF QGEIPQEAKG QPVVLLIDMN GEVCLVDREG TPFQGLTNVN SEFERPLGLP
     GKRVVHITSC SAGGERIDMW GDAGCNDLFG YYRSGTLKEA VIAVCNEEMH QLYYDVEVLL
     ELAEKLPETS SRRAQVLQAL YDASLLTSDF TEEEMVKARS LLAEQLSKQN GDVSLTVSAV
     GHAHLDLAWL WPLRETIRKG ARTFSTALRM MERYPDYIFG ASQPQLYQWI KDNYPKLYKQ
     IKDRIAEGRW EIQGAMWVEP DSNISGGEAL VRQILYGQRF YQEEFGKTVD TLWVPDIFGY
     SAALPQILLK SGLKYMVTQK LSWNEHNDYP HHTFFWEGID GSRILTHLPP EDTYNSPAAP
     RSLLRIEEEY LDKNVSDRAL MLFGIGDGGG GPGEEHLERL KREQNLLGLP KVVQETSADF
     LKKLSEQQHR YQTWRGELYL EKHQGTLTSQ ARNKRYNRKM EKALRELEFA AVLAKHLCGL
     DYPGEELEGL WKETLLYQFH DILPGSSIKR VYDESITRYE SMLEKAEQLI NQCYTVLATA
     AGGEWAVFNS LPWERKEWIK VSGKWAHIQA PAMGVVRCQL NAAAGNIGAS LMAEQNCLQN
     ELLYVQFGDS GSIVSIRDKR ENRELLLPGR NGNELILFQD EGGDAWDFRD DYRLRASNVL
     KPSRSRAYLD GPTAVMEQTY EFGSSALVQQ IVLTEDSARL DFITRVDWHE KNKMLRAAFP
     LDVRCDYSSA EIQFGHIRRP VNRNTSWEAA KDEICAHQWI DLSEAGYGVA LLNDCKYGFR
     ASGSELEINL LRSSTYPDPE ADQAMHEFVY SLLPHKGDAA AARVYRAGYE LNVPLRMIQA
     EAGLKNTLIT PCLGQGFSSF VLDHDQVMIE AVKQAEDDEG VIIRLYEAAG GKANTRLRIS
     LPFRTVEAVN LVEEPVLEPQ NVVDDEVLLT FEPFEMKTLK IQF
//