ID A0A2S0URM0_9RHOB Unreviewed; 403 AA.
AC A0A2S0URM0;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Acetyl-CoA C-acetyltransferase {ECO:0000313|EMBL:AWB50447.1};
GN ORFNames=HYN69_15760 {ECO:0000313|EMBL:AWB50447.1};
OS Gemmobacter aquarius.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Gemmobacter.
OX NCBI_TaxID=2169400 {ECO:0000313|EMBL:AWB50447.1, ECO:0000313|Proteomes:UP000244496};
RN [1] {ECO:0000313|EMBL:AWB50447.1, ECO:0000313|Proteomes:UP000244496}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HYN0069 {ECO:0000313|EMBL:AWB50447.1,
RC ECO:0000313|Proteomes:UP000244496};
RA Yi H., Baek M.-G.;
RT "Genome sequencing of Gemmobacter.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR EMBL; CP028918; AWB50447.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S0URM0; -.
DR KEGG; geh:HYN69_15760; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000244496; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000244496};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:AWB50447.1}.
FT DOMAIN 5..233
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 281..402
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 359
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 389
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 403 AA; 42218 MW; 65CF99B550699255 CRC64;
MSDAFIYDAL RSPRGKGRPD GALHEITAVA LSARMLDAIA TRNGLTGAAV EDVIWGNVTQ
VGEQGGCLAR SAVLLSGLDQ AIPGLSVNRF CASGMEAVNL AAGQVRGGAG HAYIAGGVEM
MGRVPMGSDG AAIAVDPSLA MKTYFVPQGI SADLIATEYG ITREAADAYA VESQRRAALA
WEEGRFANSV IPVQDQNGLP ILDRDEYMRP GTDMQTLGAL KPAFKEMGEV MPGFDRVALM
KYPHLERIDH IHHAGNSSGI VDGAAALLIG DAEFGRAHGL RPRARIRATA KIGTDPTIML
TGPVPVTEKI LREAGMAIND IDLFEVNEAF ASVVLRFMQA FDVDPARVNP CGGSIAMGHP
LGATGAIIIG TLLDELERTG KSTGLATLCI ASGMGAATII ERV
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