ID   A0A2S0WPT4_9ACTN        Unreviewed;       368 AA.
AC   A0A2S0WPT4; A0A5F2F5B7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=GuaB3 family IMP dehydrogenase-related protein {ECO:0000313|EMBL:AWB93326.1};
GN   ORFNames=C3E78_14520 {ECO:0000313|EMBL:AWB93326.1}, E4L97_04545
GN   {ECO:0000313|EMBL:TGN34316.1};
OS   Aeromicrobium chenweiae.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Aeromicrobium.
OX   NCBI_TaxID=2079793 {ECO:0000313|EMBL:AWB93326.1, ECO:0000313|Proteomes:UP000244384};
RN   [1] {ECO:0000313|EMBL:AWB93326.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=592 {ECO:0000313|EMBL:AWB93326.1};
RA   Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000244384}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=592 {ECO:0000313|Proteomes:UP000244384};
RA   Li J.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:TGN34316.1, ECO:0000313|Proteomes:UP000297606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S592 {ECO:0000313|EMBL:TGN34316.1,
RC   ECO:0000313|Proteomes:UP000297606};
RA   Li J., Ha Z., Lu H., Jin N.;
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC       {ECO:0000256|ARBA:ARBA00005502}.
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DR   EMBL; CP026952; AWB93326.1; -; Genomic_DNA.
DR   EMBL; SRPI01000001; TGN34316.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S0WPT4; -.
DR   KEGG; aez:C3E78_14520; -.
DR   OrthoDB; 9805398at2; -.
DR   Proteomes; UP000244384; Chromosome.
DR   Proteomes; UP000297606; Unassembled WGS sequence.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR   CDD; cd00381; IMPDH; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR005990; IMP_DH.
DR   InterPro; IPR005992; IMP_DH-rel2.
DR   InterPro; IPR001093; IMP_DH_GMPRt.
DR   NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR   PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR   Pfam; PF00478; IMPDH; 1.
DR   SMART; SM01240; IMPDH; 1.
DR   SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE   3: Inferred from homology;
FT   DOMAIN          15..299
FT                   /note="IMP dehydrogenase/GMP reductase"
FT                   /evidence="ECO:0000259|Pfam:PF00478"
SQ   SEQUENCE   368 AA;  39203 MW;  4F3EE0368E6E3821 CRC64;
     MADIEIGTAK RGRRAYSFDD IAIVPSRRTR DPEEVSTAWQ IDAYRFELPV IAAPMDSVMS
     PETAIALGRH GGLGVLDLEG LWTRYENPEE LLDEVARIEG PLATKRLQEI YAEPIKAELI
     TARLQQMRES GVTVAGSLSP QRTKQFADAV VDAGVDLFFI RGTTVSAEHV SGQTEPLNLK
     EFIYELDVPV VVGGCATYQA ALHLMRTGAA GVLVGFGGGA AHTTRSVLGI SVPMASAVAD
     VAAARRDYLD ESGGRYVHVI ADGSIGRSGD IAKAVACGAD AVMIGSPFAR AVEAPGRGFH
     WGAEAWHPDL PRGERVDIGT VGDLESVLFG PSSVPDGTMN IIGALRRAMA TTGYTDLKEF
     QRVEVVVG
//