ID   A0A2S0WQ05_9ACTN        Unreviewed;       945 AA.
AC   A0A2S0WQ05; A0A5F2F1S5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=FAD-binding oxidoreductase {ECO:0000313|EMBL:AWB93406.1};
GN   ORFNames=C3E78_14945 {ECO:0000313|EMBL:AWB93406.1}, E4L97_04970
GN   {ECO:0000313|EMBL:TGN34398.1};
OS   Aeromicrobium chenweiae.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Aeromicrobium.
OX   NCBI_TaxID=2079793 {ECO:0000313|EMBL:AWB93406.1, ECO:0000313|Proteomes:UP000244384};
RN   [1] {ECO:0000313|EMBL:AWB93406.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=592 {ECO:0000313|EMBL:AWB93406.1};
RA   Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000244384}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=592 {ECO:0000313|Proteomes:UP000244384};
RA   Li J.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:TGN34398.1, ECO:0000313|Proteomes:UP000297606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S592 {ECO:0000313|EMBL:TGN34398.1,
RC   ECO:0000313|Proteomes:UP000297606};
RA   Li J., Ha Z., Lu H., Jin N.;
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; CP026952; AWB93406.1; -; Genomic_DNA.
DR   EMBL; SRPI01000001; TGN34398.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S0WQ05; -.
DR   KEGG; aez:C3E78_14945; -.
DR   OrthoDB; 9770306at2; -.
DR   Proteomes; UP000244384; Chromosome.
DR   Proteomes; UP000297606; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   Pfam; PF02754; CCG; 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
FT   DOMAIN          41..259
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   DOMAIN          598..631
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   945 AA;  100638 MW;  03738B94519813D9 CRC64;
     MVTITDATTT DVVAELGRLG VADVDDSTLT RALYSTDASL YRVVPRVVVR PRSTEEVLAT
     VAACRTTGVP LTSRGAGTSI AGNAVGPGVV LDFTRHLNRV LDIDVEARTA RVEPGTVHAV
     LQKAATPLGL RFGPDPSTHT RCTVGGMIGN NACGSRALAY GRTADNVVGL DVVTMRGEEL
     TLGHGASATP SSTLDDLRSL VGANLSTVRT ELGTFGRQVS GYSLEHLLPE NGFDVARFMA
     GTEGTLATMT STTVRLVQDP PHRQVLVLGY ASMAEAADDV PALLPFGPTA CEGLDSRIVD
     VYRTHRGTVP DLPRGQGWLF VEISGEVPAE IADTVAQAAR AASALDHRVV TDGGEQAVLW
     RIREEGAGLA TRTLPGKALS GWEDAAVPPE KLGRYLRELD ALLRENDLDG VPYGHFGDGC
     VHIRIDFPLD AEGGHQVFRR FLTDAATQVA SLGGSLSGEH GDGRARSELL PLMYSGEAIS
     LFEQVKAVLD PDDLLNPGVL VRPAAVDADL RGPESIHSPG REHLSRRLGL RLLHDDGDLG
     KAVHRCTGVG KCIADNAGSN GVMCPSFQAT REEKDSTRGR ARVLQEMIDG RLVTGGFRAP
     EVHEALDLCL ACKGCLNDCP TGTDMASYKS EVLHQSYEGR LRPRSHYVLG RLPFWARVTA
     PVAWLANLGL RTPGLRSVAR WVAGVDQRRS LPAFATRRFS RTARPVRTDD RPRVVIWADS
     FTEYFSTDGG QAALRVLDGA GYDVEVLGRP QCCGLTWITT GQLDTARTMI GRAIEQLHPY
     VAAGVPVVGL EPSCLAVLRS DAVELVDDPR AVEVAQGVFT LSELLQRTEG WRPPDLTGTT
     LVVQPHCHQA SVLGFEADLA VMTATGATID RVSGCCGLAG NFGVEKGHYE VSVAVAEQQL
     MPAVRNAPAG ALVVADGFSC RTQLDDLAAV QAVHLAQVLD SATAR
//