ID A0A2S1YVG8_9ACTN Unreviewed; 644 AA.
AC A0A2S1YVG8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Cell division protein {ECO:0000313|EMBL:AWK08091.1};
GN ORFNames=DDQ41_03080 {ECO:0000313|EMBL:AWK08091.1};
OS Streptomyces spongiicola.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1690221 {ECO:0000313|EMBL:AWK08091.1, ECO:0000313|Proteomes:UP000245051};
RN [1] {ECO:0000313|EMBL:AWK08091.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HNM0071 {ECO:0000313|EMBL:AWK08091.1};
RA Zhou S., Huang X.;
RT "Complete genome sequence of the Type Strain of Streptomyces spongiicola
RT HNM0071, the producer of staurosporine.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP029254; AWK08091.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S1YVG8; -.
DR KEGG; sspo:DDQ41_03080; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000245051; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:AWK08091.1};
KW Cell division {ECO:0000313|EMBL:AWK08091.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 88..257
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 303..618
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 68297 MW; 695AD143E4E1C960 CRC64;
MPVPARRGGP AGRGRPAPRP RRTAPPRRPA APGRIRLGNP RPRLRLVSLA LTLVMLAFVV
RLLQVQAVDA GTYAAMAEKN RYTSHTLAAE RGRITDRAGI ALATSVDAHD ITADPKMFTP
EESRAPDAPE QAAALLAPIL GADPAVLANK LKAPKSRYTV LARRQTPQVW KQIKDLKGAF
AEKAAADRTR GGPGANVLAG VFQESSSKRV YPNGDLAAGI LGWVNAEGRG AGGLESMLDK
ELAGRDGSIT YAQSGGRRVP TAGTREKPAV PGSDIELTID RDIQWAAQRA ISEQVAKSKA
DRGYVLVQDT RTGEVLAMAN APGFNPNDIS RADVAAMGNA ALQDVYEPGS TSKVMSIAAV
LEERAATPAT HVTVPNRLHR GDRLFKDDVD HPTWYLTLNG VLAKSSNIGT ILATGQLGKT
QAQANRVLYS YLRKFGIGSP TGLGYPGESP GILAEPQDWS TSQQYTIPFG QGLSINAMQA
ASVYSTIANG GVRVEPTLVR GTRGPGGRFV PAQTPERTRV VSEKTAKTLA TMLESVVGNE
EGTGTRARIP GYRVAGKTGT ANRVDPELGR YRGYTASFAG FAPADKPRIT VYCAIQNPTR
GSYFGGQICG PVYKKVMEFA LKTQQVAPTG AAPARLPVSF DPGA
//
