ID A0A2S1Z185_9ACTN Unreviewed; 395 AA.
AC A0A2S1Z185;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Sortase {ECO:0000313|EMBL:AWK10144.1, ECO:0000313|EMBL:GBQ00892.1};
GN ORFNames=DDQ41_15960 {ECO:0000313|EMBL:AWK10144.1}, SSP531S_23150
GN {ECO:0000313|EMBL:GBQ00892.1};
OS Streptomyces spongiicola.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1690221 {ECO:0000313|EMBL:AWK10144.1, ECO:0000313|Proteomes:UP000245051};
RN [1] {ECO:0000313|EMBL:AWK10144.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HNM0071 {ECO:0000313|EMBL:AWK10144.1};
RA Zhou S., Huang X.;
RT "Complete genome sequence of the Type Strain of Streptomyces spongiicola
RT HNM0071, the producer of staurosporine.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GBQ00892.1, ECO:0000313|Proteomes:UP000265354}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=531S {ECO:0000313|EMBL:GBQ00892.1,
RC ECO:0000313|Proteomes:UP000265354};
RA Dohra H., Kodani S.;
RT "Whole Genome Shotgun Sequence of Streptomyces spongiicola strain 531S.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP029254; AWK10144.1; -; Genomic_DNA.
DR EMBL; BGZL01000005; GBQ00892.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S1Z185; -.
DR KEGG; sspo:DDQ41_15960; -.
DR OrthoDB; 5242879at2; -.
DR Proteomes; UP000245051; Chromosome.
DR Proteomes; UP000265354; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd05830; Sortase_E; 1.
DR Gene3D; 2.40.260.10; Sortase; 1.
DR InterPro; IPR005754; Sortase.
DR InterPro; IPR023365; Sortase_dom-sf.
DR InterPro; IPR042003; Sortase_E.
DR NCBIfam; NF033747; class_E_sortase; 1.
DR NCBIfam; TIGR01076; sortase_fam; 1.
DR Pfam; PF04203; Sortase; 1.
DR SUPFAM; SSF63817; Sortase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 183..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 294
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT ACT_SITE 363
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ SEQUENCE 395 AA; 42768 MW; CE1A0DF0FE7624E8 CRC64;
MSGEGGPPWY RAPEVPGQRG PQQSAPQEWP DRGHHPGAAY QEDWYGQQAY PEAAERSRDQ
VRYRTETAAD SGYPPRPDRG AHHPTAVVAS PFPPSGEYLP SGDTGAGPQA PGTGPSEPGQ
PTGGRAERRR AAKAQGRGRR RRAPTVPPPA PKPSQTGAPL SRVEARRAAR AAKDSPAVIA
SRAFGELFIT IGVLMLLFVT YQLWWTNILA GQQANAAANK IQDEWAKGRA PGEFEPGQGF
AIMHIPKLDV VVPIAEGIDK QQVLDRGMVG HYAEGGLKTA MPEDRQGNFA VAGHRNTHGE
PFRYINQLTQ GDPIVVETQD MYYTYEMRNI LPQTPPSNIG VIAPVPAGSG FTGPGRYITL
TTCTPEFTST YRMIVWGKMV EERPRGKGKP DALVG
//
