ID A0A2S1Z984_9ACTN Unreviewed; 382 AA.
AC A0A2S1Z984;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN ORFNames=DDQ41_10190 {ECO:0000313|EMBL:AWK12833.1};
OS Streptomyces spongiicola.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1690221 {ECO:0000313|EMBL:AWK12833.1, ECO:0000313|Proteomes:UP000245051};
RN [1] {ECO:0000313|EMBL:AWK12833.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HNM0071 {ECO:0000313|EMBL:AWK12833.1};
RA Zhou S., Huang X.;
RT "Complete genome sequence of the Type Strain of Streptomyces spongiicola
RT HNM0071, the producer of staurosporine.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
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DR EMBL; CP029254; AWK12833.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S1Z984; -.
DR KEGG; sspo:DDQ41_10190; -.
DR OrthoDB; 5143400at2; -.
DR Proteomes; UP000245051; Chromosome.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AWK12833.1};
KW Transferase {ECO:0000313|EMBL:AWK12833.1}.
SQ SEQUENCE 382 AA; 41985 MW; E216F3DC6108656C CRC64;
MASRLKESGA LTSDWLPTFA AVPRELFVPD LMWPGRAKGT GAGQGEAIDR NEDPEAWFSA
VYSDVSLTTQ WDDGQHSGTG KGRTPTCSNS QPSMVFSMLD ALDVQETSRV LEIGTGTGWN
AALLSERVGP GNVVSVEVDE ENAKSARERI ESAGYHPTLI VGDGFEGHRE GAPYDRVLVT
AALTEVPHRV IGQVRTGGII VAPYATTYGG EGVVQLTVQR DGSAVGHFVG SSAFMRLRQQ
RQKRRHVRDY LGGKPWPADG EKSMTTISPE EVGDWLPMFA IGLQTQGMFP WAEYYDDGTY
TLWLRDAAVT SWATVDYEPG RDEFEVYQSG PRDLWDEVAV AYLHWDNMGR PEFGRFGLTV
DGETGEHTPW LDHPSSPLRP VC
//
