ID   A0A2S1Z9U8_9ACTN        Unreviewed;      1540 AA.
AC   A0A2S1Z9U8;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:AWK13112.1};
GN   ORFNames=DDQ41_24265 {ECO:0000313|EMBL:AWK13112.1};
OS   Streptomyces spongiicola.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1690221 {ECO:0000313|EMBL:AWK13112.1, ECO:0000313|Proteomes:UP000245051};
RN   [1] {ECO:0000313|EMBL:AWK13112.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HNM0071 {ECO:0000313|EMBL:AWK13112.1};
RA   Zhou S., Huang X.;
RT   "Complete genome sequence of the Type Strain of Streptomyces spongiicola
RT   HNM0071, the producer of staurosporine.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP029254; AWK13112.1; -; Genomic_DNA.
DR   KEGG; sspo:DDQ41_24265; -.
DR   OrthoDB; 9815222at2; -.
DR   Proteomes; UP000245051; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17922; DEXHc_LHR-like; 1.
DR   CDD; cd18796; SF2_C_LHR; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:AWK13112.1};
KW   Hydrolase {ECO:0000313|EMBL:AWK13112.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          32..225
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          268..447
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1540 AA;  163573 MW;  59320C6CCAE7D3FE CRC64;
     MVGSALDTFA PATRGWFTGA FSAPTAAQEG AWRAIGRGSD VLVVAPTGSG KTLAAFLAAL
     DGLTSAPPPA ETGKRCRVLY VSPLKALAVD VERNLRSPLT GIRQEAVRLG LPEPEVRVGI
     RSGDTPAAER RALATRPPDI LITTPESLFL MLTSSAREAL GGVETVIVDE VHAVAGTKRG
     AHLALSLERL DELLPRPARR IGLSATVRPV DEVARYLSPG RRAEVVQPPS GKEFDLSVVV
     PVEDMGELGG SPASEPDGAG EKPSIWPQVE ERIADLVQAH RSTIVFANSR RLAERLCNRL
     NEIAYERAVG EPLPDGAPPA EVMAQSGAAR GAPPLLARAH HGSVSKEQRA LVEEDLKAGR
     LPAVVATSSL ELGIDMGAVD LVVQVESPPS VASGLQRVGR AGHQVGAVST GVVFPKYRGD
     LVQAAVVTER MRTGSIESLR VPANPLDVLA QQLVAMVALD TWQFDDLLAV VRRAAPFASL
     PESAFTAVLD MLAGRYPSDA FAELRPRVVW DRVAGTVTGR PGAQRLAVTS GGTIPDRGLF
     GVFLAGADPR KGGGRVGELD EEMVYESRVG DVFTLGTTSW RIEDITRDRV LVSPAPGVPG
     RLPFWKGDQL GRPLELGRAV GAFLREIGSL SEEDARLRLM TAGLDGWAAG NVLSYLDEQR
     RACGHVPDDR TIVVERFRDE LGDWRVVVHS PFGAQVHAPW ALALGARLSE RYGVDAQVMH
     ADDGIVLRLP DADLMGLDLL DQDPVHLDTS YDGDQAPVGA GDTLFDKGEI GQIVTDQVGG
     SALFASRFRE CAARALLLPR RNPGKRTPLW QQRQRAAQLL QVASEFGSFP IVLEAVRECL
     QDVFDVPGLE ELMGDIESRR VRLVEVTTPE PSPFARSLLF GYVAQFLYEG DSPLAERRAA
     ALSLDSRLLA ELLGQAELRE LLDADVLGGL ERELQWLTDD RRVKDVEGVA DLLRVLGPLT
     TGELTERGAD PGWPEELAGT RRAIRVRIAG AEHWAAVEDA GRLRDALGTA LPVGVPEAFT
     EPVKDPLGDL LARFARTHGP FTSSQAAARF GLGAAVTDGA LQRLAAAGRV VQGEFHPSGI
     GQEWCDAAVL RRLRRRSLAA LREELEPVPP AALAAFLPQW QHVGGGSLRG IDGLARAVEQ
     LQGAPVPASA LEKLILPSRV AGYAPGMLDE LTTTGEVVWA GAGALPGKDG WVSLYHADAA
     PLLLPRPHPL ELTALHESVL RTLAGGYGLF FRHIADQVRA TTHPEITDPQ LADALWELAW
     SGRLTNDTLA PLRSLLGSGR TAGSTAHRAR RTVPRGRYGS LTAAARTASR NGPPTVSGRW
     SLPPAHEPDP THRAHALART LLDRHGVVTR GAVAAEGVEG GFSATYRVLS AFEDSGQARR
     GYVVEGLGAA QFAMDGAVDR LRAAAGARER AGGPTAARAL VLAAADPANA YGAALSWPEP
     PVGASHKPGR KAGSLVVLVD GELTLYLERG GKTLLSWPSE PDDPALRAAA GALAEAGAAG
     MLGTITIERI NSSAALTSPL SPLLEESGFH ATPRGLRIRA
//