ID A0A2S2DT74_9BACT Unreviewed; 287 AA.
AC A0A2S2DT74;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU003915};
DE EC=5.2.1.8 {ECO:0000256|RuleBase:RU003915};
GN Name=fkpA {ECO:0000313|EMBL:AWL08499.1};
GN ORFNames=EWU22_04950 {ECO:0000313|EMBL:TBH75899.1}, HME7025_00627
GN {ECO:0000313|EMBL:AWL08499.1};
OS Aquirufa nivalisilvae.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae; Aquirufa.
OX NCBI_TaxID=2516557 {ECO:0000313|EMBL:AWL08499.1, ECO:0000313|Proteomes:UP000245468};
RN [1] {ECO:0000313|Proteomes:UP000245468}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HME7025 {ECO:0000313|Proteomes:UP000245468};
RA Kim H., Kang H., Joh K.;
RT "Pseudarcicella sp. HME7025 Genome sequencing and assembly.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AWL08499.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HME7025 {ECO:0000313|EMBL:AWL08499.1};
RX PubMed=31433289;
RA Kim H., Kang H., Joh K.;
RT "Allopseudarcicella aquatilis gen. nov., sp. nov., isolated from
RT freshwater.";
RL Int. J. Syst. Evol. Microbiol. 69:3574-3580(2019).
RN [3] {ECO:0000313|EMBL:TBH75899.1, ECO:0000313|Proteomes:UP000292948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=59G-WUEMPEL {ECO:0000313|EMBL:TBH75899.1,
RC ECO:0000313|Proteomes:UP000292948};
RA Pitt A.;
RT "Genome of a new Bacteroidetes strain.";
RL Submitted (FEB-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC ChEBI:CHEBI:83834; EC=5.2.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00000971, ECO:0000256|PROSITE-
CC ProRule:PRU00277, ECO:0000256|RuleBase:RU003915};
CC -!- SIMILARITY: Belongs to the FKBP-type PPIase family.
CC {ECO:0000256|RuleBase:RU003915}.
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DR EMBL; CP029346; AWL08499.1; -; Genomic_DNA.
DR EMBL; SEWX01000002; TBH75899.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S2DT74; -.
DR KEGG; psez:HME7025_00627; -.
DR OrthoDB; 9814548at2; -.
DR Proteomes; UP000245468; Chromosome.
DR Proteomes; UP000292948; Unassembled WGS sequence.
DR GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.50.40; -; 2.
DR InterPro; IPR046357; PPIase_dom_sf.
DR InterPro; IPR001179; PPIase_FKBP_dom.
DR PANTHER; PTHR10516; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE; 1.
DR PANTHER; PTHR10516:SF464; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP12; 1.
DR Pfam; PF00254; FKBP_C; 1.
DR SUPFAM; SSF54534; FKBP-like; 2.
DR PROSITE; PS50059; FKBP_PPIASE; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|PROSITE-
KW ProRule:PRU00277}; Reference proteome {ECO:0000313|Proteomes:UP000245468};
KW Rotamase {ECO:0000256|ARBA:ARBA00023110, ECO:0000256|PROSITE-
KW ProRule:PRU00277}.
FT DOMAIN 206..287
FT /note="PPIase FKBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50059"
SQ SEQUENCE 287 AA; 30792 MW; F1D66F39900371E4 CRC64;
MRKQLIGLLS AVVFLSACNQ NKVEVIDGVK IQFHSHDDKA KKLKDGDIIT FGLVIKNSTD
SVLQDTYKEG KPGKGMIQAP NNAPGSFKGT FENGLRLLAL GDSATILVPI DSLTKNIQAP
LPPFLKPGSD LKYTVKVLKV QSRAEFEKEM EKEAAVNKQA AAGKLAQEPK VIADYIAKSG
KTFQKSASGL YYSILSPGAG VAAKMGDTWT VNYRGSFVDG KEFDKGSAAE MPLGQMIPGF
NEALTLLKKG GKGVFVIPSA LGYGDQERGP IPANSVLVFE VELLNKK
//
