ID A0A2S3QD83_9FIRM Unreviewed; 299 AA.
AC A0A2S3QD83;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=6-phosphogluconate dehydrogenase (Decarboxylating) {ECO:0000313|EMBL:POB09726.1};
GN Name=gnd {ECO:0000313|EMBL:POB09726.1};
GN ORFNames=CO251_15740 {ECO:0000313|EMBL:POB09726.1};
OS Sulfobacillus sp. hq2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Clostridiales Family XVII. Incertae Sedis; Sulfobacillus.
OX NCBI_TaxID=2039167 {ECO:0000313|EMBL:POB09726.1, ECO:0000313|Proteomes:UP000237334};
RN [1] {ECO:0000313|EMBL:POB09726.1, ECO:0000313|Proteomes:UP000237334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=hq2 {ECO:0000313|Proteomes:UP000237334};
RA He Q., Li Y., Han Y., Zhao W., Huang Z.;
RT "Draft genome sequence of Sulfobacillus sp. hq2.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POB09726.1}.
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DR EMBL; NWUL01000047; POB09726.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S3QD83; -.
DR OrthoDB; 9786703at2; -.
DR Proteomes; UP000237334; Unassembled WGS sequence.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR004849; 6DGDH_YqeC.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR006184; 6PGdom_BS.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR NCBIfam; TIGR00872; gnd_rel; 1.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF67; 6-PHOSPHOGLUCONATE DEHYDROGENASE YQEC-RELATED; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
DR PROSITE; PS00461; 6PGD; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064};
KW Reference proteome {ECO:0000313|Proteomes:UP000237334}.
FT DOMAIN 168..295
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
SQ SEQUENCE 299 AA; 32323 MW; 67AF3E0126F5D583 CRC64;
MKIGMIGLGR MGGNMVKRLT QNGHEVVAYD RSPDAVTEIA KSTGAVGAAS IPDLVNKLEG
RRVVWMMVPS GDPTEQTLET LLSLLSPGDI IIDGGNSNFR DSMRRAKLAH AQQIEFIDSG
TSGGVWGLAN GYCLMVGGSD DAVHYCEPIF TTLAPEDGYL HTGAVGSGHF VKMVHNGIEY
GLLQAYAEGF EILKESQFPL DLPAITKLWN HGSVVRSWLL ELLEDAYAKN PGLKDIRGYV
EDSGEGRWTV QEAINENVPA PVITASLFAR FASRQEESYG AKVIAALRNE FGGHAVKTE
//
