ID A0A2S3QHP2_9FIRM Unreviewed; 1277 AA.
AC A0A2S3QHP2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CO251_06265 {ECO:0000313|EMBL:POB11142.1};
OS Sulfobacillus sp. hq2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Clostridiales Family XVII. Incertae Sedis; Sulfobacillus.
OX NCBI_TaxID=2039167 {ECO:0000313|EMBL:POB11142.1, ECO:0000313|Proteomes:UP000237334};
RN [1] {ECO:0000313|EMBL:POB11142.1, ECO:0000313|Proteomes:UP000237334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=hq2 {ECO:0000313|Proteomes:UP000237334};
RA He Q., Li Y., Han Y., Zhao W., Huang Z.;
RT "Draft genome sequence of Sulfobacillus sp. hq2.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POB11142.1}.
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DR EMBL; NWUL01000030; POB11142.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S3QHP2; -.
DR Proteomes; UP000237334; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.450.40; -; 3.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF84; SIGNALLING PROTEIN WITH EAL DOMAIN; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF13185; GAF_2; 3.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 3.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000237334}.
FT DOMAIN 765..900
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 904..1161
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1277 AA; 143490 MW; FD50A05F13A55942 CRC64;
MNKCYLLITT GSQPRRSCYR EIRLEHVGEI KMSSIVWWDD DDNAILATID WDEIAALIAQ
TLADNGVGSE QVQWIVNQVP QFRYPPGSPE DQHRMRQAVQ LFIERHQSVE LYIEAYPRLA
QVLQRHLPVS VGPVALNRLI ADLVLLAEAY LPRIEYERSR MIQAYRTVVT MNGEIGKAQD
PIHLYHMLCE VAVRVGGMRL AWVGMADARS GFVRVVAQAG DIRYLEELRR PEQDDLLDLP
LDRLGVPALE ALHQGQPQFI NRLGPDLPRI IRRRLQQYHL GSGAALPIRV RGRVEAVFAV
YHQEQDYFDA PMRGLLKELI VSAEEGLDRL WAQQAELAAH REQAQLAQHL RDVSALNSVL
AETNQILPTL DSSFQVYETV CRILVERGKM ALAWVGVPSR DGFVRVVAAV GETHYLSAMR
RPGHPKQVAI SWQPGRPESL GPTGHALMTG QPQFVDVVDY PPKGIDMRPW RDWLNRFSLR
SSAALAIRHG SHVAAVLTVY HRQMVGFNPE LQTLLKELVV DIEEGIRRIG LQRSERVARQ
RLSRTVTTLL ELQNLYRSLL RQGDTILQAK TADEILTSSC ERLVEGGLFL VAWVGQPVEN
APSLRWRFLA IAGPGQDANQ KFTPFFDHSP VPPPEAAWQS QQPVSHPDLA SDPVMPDTLR
QFFEEIGGRA AASIPLRRGG QRYAVLTVIS AKPHAMTDKI MELLSHIGDL MSHGLDALDA
RNRLEQSQQQ AWDLAHHDPL TGLPNRLWLA DYLPQALKRA EAEGRQLAVG MIDLDDFKTV
NDTWGHDHGD RVLQIVAQSL SRRLAGHGHL VRLGGDEWLM VLEPDHTVTL EALLKGMSHE
LNAPIPVSAD VRVKVGASAG IAYFPDDARE AETLIRLADI ALYQSKAQKG QRSQWVVRYQ
PLTRQLPEHQ PGVPFQFTLD QVVVVYQPIV DLATGAVQEV EALARLQMGE RILGPAEFLT
RLSSDEQYQL SLTVLEQALS QWQRWYRHDH LDLMIGVNFA ASDFLRTGFV EAIASRLEAS
GVPPQRLVLE ILEEDEFLSL PRAKGQLASL KHLGVQIALD DMGRAYASLF RLAELPIDII
KIDQGFMRDL ERHPHNIRLV AALMQIADFM RLKLVIEGVE TVPVRDAIRL MARQQVPAVQ
GYVFSRPVPP DEIVAVGHLG YQIPPVPTIG PDQWFLAYAR RVVFQEAFSG MVYYAPGLLD
IDKVSDLHAC HLNPSFIHDP RLTPVYEELH REMARWASHA GNVAVMQHVS QLEVELLSRL
ESLILTRGAT LDGLPTA
//
