ID   A0A2S4HEE7_9GAMM        Unreviewed;       399 AA.
AC   A0A2S4HEE7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:POP52366.1};
GN   ORFNames=C0068_12595 {ECO:0000313|EMBL:POP52366.1};
OS   Marortus luteolus.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales;
OC   Spongiibacteraceae; Marortus.
OX   NCBI_TaxID=2067667 {ECO:0000313|EMBL:POP52366.1, ECO:0000313|Proteomes:UP000237222};
RN   [1] {ECO:0000313|EMBL:POP52366.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ZX-21 {ECO:0000313|EMBL:POP52366.1};
RA   Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC       {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POP52366.1}.
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DR   EMBL; PQGG01000029; POP52366.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S4HEE7; -.
DR   OrthoDB; 9764638at2; -.
DR   Proteomes; UP000237222; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020610; Thiolase_AS.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR   PANTHER; PTHR43365; BLR7806 PROTEIN; 1.
DR   PANTHER; PTHR43365:SF1; STEROID 3-KETOACYL-COA THIOLASE FADA6; 1.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00737; THIOLASE_2; 1.
DR   PROSITE; PS00099; THIOLASE_3; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000256|RuleBase:RU003557};
KW   Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:POP52366.1}.
FT   DOMAIN          5..223
FT                   /note="Thiolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00108"
FT   DOMAIN          277..398
FT                   /note="Thiolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02803"
FT   ACT_SITE        91
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT   ACT_SITE        355
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT   ACT_SITE        385
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ   SEQUENCE   399 AA;  42325 MW;  75E8CB28AEA6C4F8 CRC64;
     MAEAFIYDAI RTPRGKGKRG GSLYEVKPID LVTNLLEALK DRNDLDTTKV EDLILACGEP
     VKEQGQNIAK AALVYSSWDD VTTGAQLHRF CAGGLDAVNM AAAKVAAGYE DLVAAGGVES
     MSRLGIGASG GATGDPWVAM KSYFISQGLG ADMIATMDGF SREDVDRYAV MSQQRAAQAR
     DKGYFKSIVP VRDFNGVTIL DHDEFIRGDT SLDGLAKLKP AFQMFNDFGH GGVAKLKYPE
     LENIHCVHTP GNSSGIVDGA GLVLVGSERA GKEQNLTPRA RILSCALVGT EPTIMLTGPA
     PATEKALKKA GLSVDEIDLF ELNEAFASVV LRYQRTLNIP DEKINVNGGA IAMGHPIGAT
     GAMILGTLLD ELERRNLKRG VVTLCAGGGI GIATVIERV
//